TBYPANOSOMIASIS IN THE ANGLO-EGYPTIAN SUDAN 139 



from spleen, liver, stomach surface, blood of vessels of stomach, lung's and heart's blood, no 

 trace of trypanosome infection was detected. 



There was no ulceration of the stomach, but the gastric vessels were engorged. At one 

 point there was a congestive patcli on tlie mucous membrane. 



Exp. 13. Dog 5. A pariah suggesting tuberculosis. 



Mitrch IStli. Inoculated subcutaneously with about 2'5 c.c. bluod from Dog 4. 



March 2'2n(I. Blood examined. No trypanosomes present. 



Mdir/i 23^'/. Blood examined. Trypanosomes present, about 12 per microscopic field, 

 nearly all long forms and very lively. The incubation period was, therefore, 5 days. This 

 dog was treated by injections of chrysoidine intravenously and its case thus falls to be 

 described when treatment is considered (p. 156) bvit the post-mortem examination was very 

 interesting and the results may be here described. 



April l.s/. Animal in a dying condition in the evening, chloroforiueil ami kept in the 

 ice chest till the following morning. 



April 2wl. Autopsy perfornu^d, no external signs except emaciation. 



Stotmirh. — -The vessels passing to and from the lesser curvature and distributeil 

 externally upon the stomach well were much eugorgetl. The gastric contents consisted of 

 altered blood and glairy mucus. There was no ulceration, but along the ridges of several 

 of the ruga; there were areas of congestion presenting a dull red tedematous appearance. 

 Smears from these shewed spirilla similar in every respect to those shewn in Fig. c. 



Smears from the stomach contents also shewed spirilla. No trypanosome forms 

 present. 



Infest inrs. — Full of altered blood and mucus. Beyer's patches congested, exhibiting 

 an appearance somewhat like that seen in early enteric, approaching to the " shaved beard " 

 aspect. There was no ulceration. 



A smear from the surface of a congested patch shewed neither spirilla nor trypanosomes. 



There was great enlargement of the mesenteric glands, especially in the appendicular 

 area where there was a regular buncli of them, the largest being 3 inches in length. On 

 section they shewed no caseation, but as they may prove to be tubercular, they were put 

 aside for microscopical examination. 



Lnnjr I/ifestiiir. — Wholly unaffected. 



Spleen. — Large and congested smear. No signs of trypanosomes. 



Liver. — Also large and congested. Smear shewed numerous curious involution forms 

 probably due to the treatment adopted. 



Kiihiei/x. — Slight congestion . 



Brain. — Engorgement of superficial vessels. Some excess of cerebro-spinal lluid. 

 Smear of fluid made. No trypanosomes present. 



JJoiie niarroir. —Dark red in colour. Smear, negative. 



Lungs. — Smear, negative. 



Heart's blood. — Smear, negative. 



The absence of trypanosomes in all the smear preparations except the liver is a peculiar 

 and interesting fact. 



Compare with the findings in Exp. 6. 



Exp. 14. Gerbil 2. 



March 4:th. Inoculated intraperitomally with a few drops of blood from Dog 4. 



March 1th. Trypanosomes found for the first time in blood taken from the tail. 



