142 TRVPANOROMIASIR IN THE ANOLO-KOYPTIAN SUDAN 



f.lriT, Sftlieii mid Luiiijs. — Smears showed onliimry trypiinosonifs iiinl splicrical mul 

 oil<ily-sliu|HMl iiiV()hitii)ii forms. Tin' s|ilciii was I iiicli in It-n^'tli. tlu* fjerbil from simiit to 

 root of tail 4 inrlu's. 



('trelnii-S/iiniit Fliiiil. — Miiliv t rvpaiiosoiiii's wtTr fciMiid ; a l)inl-slia|iiM| furiii with it 

 iiiU'hMis mich'rgoing st'gmfiifutioii was initid. IMati- XI\'., l-'i^^. r. 



lioiie-uKirroir. — No trypunosomi'S present. 



Exp. 17. Monkey 4 {t'l-no/'il/nrus i>ii/i<rii.i). Weight 24 kilos. 



Miiri-li '11 til. Inoetihiteil siihcutaneously witli 1 c.e. lihjoil from I)og f). 



Trvpanosomes of I'oth kimls fouml for tlie first time on April Mnl. 



.l/-/;7 5///. Treatment with blood serum eonnneneeil ((•/<//' p. Kiti). 



K.xji. 18. (Terbi! 11. No liasophiliu present in the erytliroeytes. 



Afiirc/i 'liit/i. Inoeuhited suhiutaiieoiisly with a few drops of hlood from Dog T). 



March 29///. Both forms of trypanosome present (Fig. I'l). This animal was also 

 treated with serum ((•/</(' infra). 



The animal was found dead on .Vpril 'Mi\. Its stomach contained nematodes and 

 altered blood. 



There was some congestion at the cardiac end. 



Unfortunately a bacterial invasion of all tlie tissues had occurred, and tlie smears made 

 sliowed no trypanosome infection. 



The spleen measured 1^ inches in length wiiile the gerbii from snout to root of tail 

 was 4J inches. 



Kxp. 19. Jerboa 8. The blood contained a few Inemogregarines. 



Miiri/t '22)1(1. Inoculateil sulieutaneously with a few drops of blood from Gerbii '2. 



Miircli '2f)tli. Trvpanosomes present, four or five per microscopic Held. Very typical 

 long and short forms. Emaciation set in, and the jerboa died on the morning of Marcli 28tli. 



An autopsy was at once performed. 



StoiiKirh. — Ulcerated, tliere being several small Inemorrhagic erosions, and, in addition, 

 tiny areas of congestion. There was the same sticky, coffee-coloured mucus present, as in 

 Dog 4 and the other cases quoted. 



Smears were made botli of tlie blood clot covering the largest ulcer, ami from the surface 

 of tlie ulcer itself. 



The same condition of things was found in both, i.e., (</) ordinary short trypanosomes ; 

 (/<) involution forms of various kinds ; {<■) the curious small " ruddy " forms which were present, 

 in Gerbii 8 (Exp. 16). The intense staining of their relatively large nuclei, and centrosomes 

 was again evident. Some trypanosomes looked as though they liad undergone involution, 

 nucleus and centrosoine remaining well marked, but the general sliaiie having entirely altered. 

 A number of these forms looked extremely like Leishnian bodies, but in none of them were the 

 short chromatin rods so characteristic of the parasites of Cachexial Fever seen. A .splierical 

 ilot, however, was present, and tliese are evidently the young forms described liy liingard.* 



The tiny " ruddy '" forms occurred in groups or singly. The largest found of a typical 

 trvpanosome shape measured 98 ft. in length, by '2 8 f. in breadth at the broadest part, i.e., 

 the nucleus. Plate XIV. ; Fig./. 



Ifi'iirl. — Hlood ; trvpanosomes present. Both forms seen, also involution forms like 

 tho.si' found in the stomach. None nf the small " ruddy " kinds seen. 



Iiiilinii Mnl. <!nvllf, C.-ilciitt,i. Si-pt. ami 0<'f., igO.V 



