158 



TRYPANOSOMIASIS I\ THK ANOLO-EOYI'TIAN SIDAN 



Leishiium-nuiiuvaii lnnlics oonsistud in tlu' luicruiiiu-k'Us or hlcpliiirupliist lu-iiig a round dot 

 and nut a small rod, like a stout bacillus, such us is found in the human parasite. 



Exp. 29. Gerbil 17. — Mini 'IQth. Hlood remarkahlf in tliat while it contained both 

 forms us usual there was a lar^^'e nunilier of curious short forms jjussessin^ numerous dots 

 of chrumatin scattered throUj^liuut their cytoplasm, spiicrical, vacuolated and granular types 

 were also present. Some were .so altered that they bore very little resemblance to 

 trypanosomes. 1 c.c. of a saturated solution of sniulilc chrvsoidine was given subcutaneously. 



.!/<(// 'llnl. Animal well. IMood swarming witii both forms of trypanosome. The 

 parasites were very active. 1 c.c. given as above. 



May 2inil. Fresh blood swarming. Many curiously broad forms with large undulating 

 membranes. No motionless parasites seen. Tlu' trypanosomes ilid not stain well. 1 c.c. 

 given as above. The animal, which seemeil ijuite well and livelv, unfortunately died during 

 the night, and was found much decomposed. 



The post-mortem examination revealed an enlargeil sjiKi ii and a brain ami spinal-cord 

 stained a brilliant viiinw. Snicars were negative as regards the presence of trypanosomes. 



Jink 



Fig. 74. — Tkmpekatirk Rf.cokii. Moskbv No. 8 



Exp. 32. Monkey S. Weight 2 kilos. — June 1th. Six or seven trypanosomes per 

 field. 1 c.c. soluble chrysoidin by intramuscular injection. 



Jutii' 8fh. Many lively trypanosomes, both long and sjuirt. Some vacuolated and 

 some exhibiting large undulating nieinbraiies. Animal had diarrhoea. A smear of the 

 fieces showed spirilla somewhat resembling those found in lesions of the stomach and small 

 intestine. 1 c.c. given as above. 



.Utiit 9t/i. Animal lively, no change seen in fresh blood film. In the stained 

 preparation many long forms in [iroctss of division were seen. JIaiiy of the short forms were 

 broad with large undulating nicnibranes and contained numerous vacuoles and chromatin 

 granules. 1 c.c. given as abovi'. 



Jiiiif \Olh. Animal lively. Blood in much the same condition. 3 c.c. given. Urine 

 markedly yellow. 



./iini' lll/i. No (hanges noted. 5 c.c. given. 



Jiiiif I'ltli. JIany dividing forms in the blooil. Appetite excellent. Urine and faeces 

 both stained. 5 c.c. given. 



Jnni' I3t/i. Jlonkey lively. Degenerating and dead forms present. Apparently only 

 the short forms aft'ected. Some strangely altered in shape. 10 c.c. given. Blood examined 

 two hours after this inoculation but no further change observed. 



June 14/A. In much the same condition. 10 c.c. given. This dose was continued 



