162 TUYPAN080MIA8I8 IN THE ANOLO-EOYPTIAN SUDAN 



negative. Glands still enlarged. No ill-effects fri)iii the clirysoidint' which was continiUMl 

 in the same doses. 



Jiiiii' 'l'•^l•ll. Very well, save for the fact that he had cleveloped condylomata on the 

 scrotum and roinid the anus. He had again to he put on anti-syphilitic treatment. 

 Kxamination of peripheral hlood negative. 



H e.e. venous blood inoculated subcutancuusly into Monkey 11 ('•''/'■ in/ni). 



Jnhr^nl. lilood count. K.R.C. M,HO(l,(IUU. 



Jieucocytes 9,(J00. 



The treatment was continued till about the middle of .Inly, when Captain Browning 

 Went 1)11 leave, and the patient was sent to the Civil Hospital to be treated for syphilis. I 

 retunieil from leave in October, and the boy again cainr under my personal observation. 

 Chrysoidine had not been given in the interval. 



(Moh,;- Mill. Looks well. Weight lltTi lbs. Glands in neik still enlarged. (Jlan.l 

 juice negative. No trvpannsDiiies idinnl in imr IiIikmI lilni, Imt a [v\\ were present in a 

 second. 



()r/,i/»'r 20///. (liven h grain Merck's chrysoidine in suspension. This was lontinued 

 ilaily diiwn to October Hist, when it was stopped because albumin was found in the urine 

 wliidi iiad become of an intense orange-yellow colour. No casts were present. |)nring the 

 interval trypanosomes were not found, but owing to press of other work the lunnber of 

 examinations was limited. 



<>rloli<-r 81.\7. After a long seanli one tryiianosome was finnid in a blood film. It 

 presented a normal a|ipraranee. Clirvsoiiline stop|icil as albumin ratiur copicjus. I'p to date 

 (December ISth) the drug has not been resnmeil. 



.Viirriii/iiT -il/i. It was noticed to-day that the glands above and behind tlu' jaw angles 

 iiad income enlarge(l. this constituting a new symptom. The boy seemed well and continued 

 so till NoveiiiliiT ]")th, when an attark of diarrliiea pullcil liini down to sonic extent. No 

 trvpanosoines had lni n loiind in his blood and the albumin was gradually disappearing from 

 his urine. Its colour also gradiuiUv lessened in intensity. No casts were foninl at any time. 



.\nr>'iii/H'r 1-illi. I)iarrh(ea checked. Weight 1(12 lbs. 



Xnninhir -l^^lli. Weight Idti lbs. Boy looks W(dl and is fatter. No trypano.somes 

 found in ju'ripheral blood. 



Nori iiilicr 'I'U/i. To-ilav the patient had fever and a headache. On examination of his 

 blood, ring forms of the malaria parasite, appanntly ijuartan from their shape ami structure, 

 were found. No trvpanosomes were present. 10 grains of c[ninine sulphate were given. 

 The malaria was probably a recrudescence of .an old attack. 



\i>ri-iiilifr 'liMli. Temperature flflS" F. 10 grains quinine given. 



Niimii/ii-r 'Ill/i. Temperature normal. JIuch better. Irine now quite free from 

 albunun, Idooil free from parasites. 



Xoii'inbfr 80//(. Gland puncture negative. Boy looks fat and well. 



IJi'ct'Hi/ier iKt. A single trypanosonic found in one film. A second film proved negative. 



/>eri'iii/iiT V}f/i. A distinct increase in size of the glands bchiml the ascending rannis of 

 the left jaw noted ; otherwise the patient seemed well and lively. 



Ihci'iiiln'i- \lili. Weight lOf)^ lbs. No trypanosomes found nor had they been present 

 since December 1st. (Jlamls still big. The case is still under observation, and I do not 

 think we can form any conclusion from it, though I have recorded it at some length. 

 Dr. Neave seems certainly to have found that a rapiil and marked decrease of 



