REPORT OF TRAVELLING PATHOLOGIST 185 



proceed down it. Our respective investigations were made, but I later received a letter from 



him telling me that he had gone on to Khartoum without finding any "fly." My No "fly' 



investigations yielded the same negative result, though much time was occupied in arriving 



at it. I had special permission from Brussels to investigate the bank of the Lado Enclave, 



but I received instructions to confine myself to the Sudan, so that I only investigated 



the right bank. 



I found no " fly " between Gondokoro and Shambc, although I was always on the look-out 

 for it and had with me a Uganda boy who had been specially trained to catch " fly," and 

 whose business it was to do so. It was only when I got to the Bahr-El-Ghazal country that 

 I found Glossina of any species. It would appear that a river with vast swamps is not a 

 suitable habitat, but that trees with water in proximity is what is preferred by these diptera. 



During the above search I made expeditions in two directions from Gondokoro, and 

 received great assistance from Capt. Tufnell, who saved me much expense.* 



Bahu-El-.Tebel. Trypanosomiasis 



Capt. Greig left the Uganda boy above referred to at Gondokoro after trypanosomes 

 had been demonstrated in the juice of his neck glands, and handed him on to me for 

 treatment. I had brought up some chrysoidine on the chance of having this opportunity, as 

 Dr. A. Balfour's experiments with this substance on mosquito larvae and bilharzia ova 

 already reported, had suggested to me that it might be useful in trypanosomiasis. 



I at once began injecting chrysoidine hypodermically, giving /jths of a grain and injections of 

 increasing to half a grain wdien I found no untoward results. As this was probably the first 

 time it had been used other than by the mouth, I had to proceed cautiously, but found that 

 it appeared to be quite harmless to the patient. f While I went and came on the aliove 

 expeditions, the boy had to remain at Gondokoro for treatment in respect to gonorrhoea and 

 syphilis, and it was in consequence of Dr. C. J. Baker's kindness in continuing the injections 

 of chrysoidine that I was enabled to carry out this experiment. 



A fortnight after the first injection, on examination of gland juice, only one trypanosome 

 was found after much searching. Many had been found previously. Subsequently Dr. Baker 

 made several examinations and found none between this time and the end of January, when 

 the boy was sent on to where I was camping on the Bahr-El-Jebel, at Luala's. Until the 

 first week in jMarch I remained on the river and inji'ctcd the patient at first every day, but 

 gradually diminished the dose to twice a week, and I often examined the gland juice without 

 result. The boy rapidly improved from the first, got fat and only suffered occasional pangs 

 from over-eating. I made a blood count in February, when the boy appeared quite well. Blood Count 



Lyniphocytes ... ... ... ... ... 486 



Lar^e Monoiinclear.s ... ... ... ... ... Gl 



Polynuclears ... ... ... .. ... ... -H- 



Eosiiiophiles ... ... ... ... ... ... 7 



Myelocytes... ... 4 



1,000 



My march from Shambi' to Meshra-El-Eek later on was rather a trying one, and the 

 boy only got his injection about once in ten days. 



• I have lately been informed that Dr. Hodtfes has found rHos.Hua palpalis at Gondokoro further inland 

 than I wont. 



t See, however, note. on p. IG'2. (A.B.) 



