CONTENTS 11 



PAGE 



Fallacies and Puzzles in Blood Examination. By the Director 109 



"Adventitious" Fallacies — Yeast Cells, I^ollrn (Jniius, etc.— Spirocliaete Forms— Parasite- 

 like Bodies — Differences between Yeast Cells uiul Parasites— BlottinK-pajier Fallacy — 

 Autogenetic Fallacies — Vacuoles — " Maraglianos '" — (iraiiules — " I'liain, duiub-bell, Hlameiit 

 auil droplet" Phenoiuena — Platelets — Hwnioconia — Free Flagella — Fallacies in Stained 

 l>lootl—,S)>iHr/('/,:e//eH— Alterations in Red Cells— Curious Appearance in Gerbil's Blood — 

 " Howell-JoUy " Bodies— Centrosonies in Bird's Erythrocytes — Unrecognised Bodies — 

 Death and Degeneration of Leucocytes — Bodies in the Extra-nuclear Protoplasm 

 of Certain Mononuclears — Sergentella hui/iiuis — "Howell and Hoii'ocks " Bodies — 

 Unidentified Parasites in Frog's Blood. 

 Hemarks on Kala-azar in the Kassala and Blue Nile Districts of the Sudan. 



By Captain L. Bousfield 127 



Summary of Tour — Table of Patients Treated -Prevalence of Bed-bugs — Duration of 1 >isea.se — 



Incidence of the Disease — Nationality of Cases — Death-rates of Towns ^Vti'ccted- -Onset of 



Disease — Physical Condition of Patients — Liver and Spleen Puncture — Atypical Bodies — 



] )iag'nosis — Types of Parasites — Blood Films from Animals — Recommendations — Appendix. 



Kala-azae Commlssion to investigate the Prevalence and Cause of the Disease 



IN THE E.vstern Sudan. 



(1) General Report. By Captain D. S. B. Thomson 143 



Tours of Inspection — Procedure in Villages — Native Information on Kala-azar — Native 



Treatment — Infection of Riverain and Inland Villages — Comparison of Number of 

 Cases in Provinces — Method of Transmission — S])leen Puncture — Age, Sex, Race and 

 Seasoual Incidence — Is the Disea.se Curable! — Bilharziosis — Reeoniinendations — 

 Conclusion — Tables of Observations. 



(2) Pathological Report. By Lieutenant W. E. Marshall 157 



Clinical Notes — Treatment — Perijjheral Blood — Presence of Leislimaii-I tcpuovau Bodies- 

 Relative Increase in Large Mononuclear Leucocytes — Other Blood (_!hanges — Relation 



of Eosinophilia to Kala-azar — Ih-ine and F;eces in Kala-azar — Search for Leisliman- 

 Donovan Bodies in Dogs and other Animals — Tables of Oliservations — Experimental 

 Kala-azar in the Grey Monkey — Infected Cases — Non-infected Cases — Presence of 

 Parasites in Blood of Infected ilonkeys — Tables of Observations — Morphology and 

 Culture of the Parasite — Possibility of Infection by the Bed-bug, Cimex lectularius 

 — Other Protozoa met ^^■ith during the Investigation — Protozoon from post mortem 

 S])lenic Puncture — Flagellated Bodies in Standing Water, in Fieces of Infected Monkey, 

 and in Soil — Conclusions — Possible Methods of Infection. 

 The Alkalinity of the Blood Serum in Kala-azar. By ("aptain R. G. Archibald 173 

 Technique — Titration of Serum a.iiuinst Standard Acid Solution — Cases 1-4— Conclusions. 



Herpetomonas lyg.ei. By Captain \\. (i. .\rchibald 179 



^Material and ^Methods Emiiloyed— Pretiagellate Stage — Post-tlagellate Stage .Metliod of 

 Infection — Culture and Animal l^lxpei'inients. 

 Case of Kala-azar treated by "OOG." \\\ the Director and Captain Ai!chibald... 185 

 Summary of the Case — Diagnosis Confirmed by Spleen Puncture — Injections Commenced — 

 Second Injection — Improvement — Effect on Parasites — Remarks. 

 Two Cases of Non-Ulcerating "Oriental Sore," better termed Leishman Nodules. 



By the Director, with Clinical Notes by Captain D. S. P.. Thomson ... 191 



Introduction — Case I — History — Clinical Examination — Blood Examination Growths — 



Morphology of Parasites — Histo-])athology of firowths — Recent Literature— Case II. is 



found to be a Comrade of Case I.— History -Clinical Examination— Blood Examination — 



Additional Notes — Treatment — Experimental Work. 



A Cask of Parasitic Granuloma in which Developmental Forms of Leishmania 



tropica were Present. By ('aptain R. G. Archibald 207 



History of Case — Study of Skin Lesions — Examination of Papules — ^Microscopical Ivxamina- 

 tion of Stained Specimens — Ditferential j'lood Count Histo iiatholog>- - Summary. 



