124 MOSQUITOES 



part of 1900 were extremely sugg-cstive in their results. 

 In the course of the investigatious, both Drs. Carroll and 

 Lazear were attacked by the disease. Dr. Carroll recov- 

 ered, but Dr. Lazear died — another of the lon^ list of 

 martyrs who have suffered in tlu^ cause of scientific 

 research. In this iircliininary work, which Dr. Heed 

 reported upon at the twenty-eighth annual meeting- of 

 the American Public Health Association, Indianapolis, 

 Ind., October 23, 1900, it was shown that eleven non- 

 immune individuals had been inoculated by the bites of 

 the species then knoAvn as Cvl c.r faHc\atas,vA\\c\i had previ- 

 ously fed upon blood of jiatients sick with yellow fever. 

 Dr. Reed was abk; to report two positive results in which 

 an attack of yellow fever followed the bite of a nioscpiito 

 within tli(^ usual period of incubation of the disease. In 

 one of the cases all other sources of infection could posi- 

 tively be exclud(Ml. The results of this preliminary work 

 were summed ui) in two conclusions : 1. Bacillus idc- 

 roides Sanarelli stands in no causative relation to yellow 

 fever, but when present should be considered as a second- 

 ary invader in this disease. 2. The mosquito serves as 

 the intermediate host for the parasite of yellow fever. 



The announcements made in this preliminary note ex- 

 cited much attcnition. The scientific standing of the in- 

 vestig-ators, as well as the positive result announced in 

 one of the cases, made the theory at once one of serious 

 importance. Medical men, however, were inclined to wait 

 for further developments bef<n'(> expressing an o]>inion. 

 Their point of view was jierhaps W(>11 summed up by the 

 J^ritiiih Miiliail Jouriud, which stated that althougrh the 



