and Laboratory Methods. 1215- 



„ , , TT . u TVT 1 J Hauck found, in agreement with 



nauck, L. Untersuchungen zur Normalen una " 



Pathologischen Histologic der Quergestreif- Other observers, that in infants the 



ten Musculatur. Deutsche Zeitschr. f. Ner- individual fibers of different Striated 

 venheilk., 17 : 57, 1900. 



muscles have practically the same 



diameter, while in adults fibers from different muscles vary greatly in diameter. 

 The thickness of the fiber is dependent upon the general nutrition of the indi- 

 vidual. Rigor mortis causes a decrease in the diameter. 



In a series of experiments upon young dogs the author studied the influence 

 of rest, work and enervation upon the size of the muscular fibers. Cutting the 

 sciatic nerve produces simple atrophy of the muscle supplied by it. The width 

 of the muscular fibers is diminished about one-half. Simple muscular inactivity 

 due to ankylosis gives the same result. j. h. p. 



Moser, A. Tuberculosis of the Heart. Med. Moser reports a case of tuberculosis 

 and Surgical Reports of the Boston City ^f ^j^g myocardium, and presents an 

 Hospital, 11: 194, 1900. ■' ' r- 



analysis of forty-five other cases col- 

 lected from the literature. In the case studied by the author, a firm yellow 

 thrombus, two cm. in size, was found attached to the wall of the left ventricle. 

 The heart muscle was yellow and fibrous. Histological examination showed 

 that the muscle underlying the thrombus was tuberculous, and that tuberculous 

 tissue was growing into the thrombus. The process apparently began with the 

 formation of subendocardial tubercles, which later fused together. Tubercle 

 bacilli were found in over half of the sections examined. 



Moser states that the following method of staining tubercle bacilli in sections, 

 devised by Mallory and Wright, is superior to the common method known as the 

 Ziehl-Neelsen : Stain lightly in alum haematoxylin ; then in steaming carbol- 

 fuchsin two to three minutes ; decolorize in one per cent, acid alcohol one-half 

 minute ; wash thoroughly in water ; dehydrate in alcohol ; clear in xylol and 

 mount. 



Birch-Hirschfeld, in reporting a similar case of tuberculous mural thrombus 

 of the heart, gave two possible modes of origin : (1) Bacilli wandered into a 

 mural thrombus, or ("2) bacilli clung to the heart wall, grew, and formed a 

 thrombus. The latter view was regarded as the more probable, as Ribbert pro- 

 duced endocarditis by injecting into the circulation particles of potato laden with 

 micrococci. j. h. p. 



Fujinami. Ueber das Histologische Verhalten Fujinami studied a large number of 



des Quergestreiften Muskels an der Grenze cases and found that both cancers and 

 bosartiger Geschwiilste. Virchow's Archiv., . , , . , , 



161: III 1900. sarcomas mvade muscle m much the 



same way. They may infiltrate be- 

 tween the separate muscle fibers ; they may press against the muscle fibers as a 

 mass ; or they may be separated from the muscle fibers by bands of connective 

 tissue, thus only affecting them indirectly. 



The infiltration by the tumor takes place through the sarcolemma sacs, as 

 well as through the tissue spaces, and through the lymph and blood vessels. 

 The invasion of the sarcolemma sac is especially marked when the infiltration of 

 the muscle is parallel to the muscle fibers, and is much more common in cancers^ 



