and Laboratory Methods. 1387 



NORMAL AND PATHOLOGICAL HISTOLOGY. 



Joseph H. Pratt. 



Harvard University Medical School, Boston, Mass., to whom all books and 

 papers on these subjects should be sent for review. 



Lewy. Die Beziehungen der Charcot-Leydenn'- Lewy shows that where eosinophihc 

 schen Krystalle zu den eosinophilen Zellen. ^^^^ abound, there Charcot-Levden 

 Zeitschr. f. khn. Med. 40: 59, 1900. . . -^ 



crystals appear. This association is 



found in all the tissues in leuksemia, in the sputum in various diseases of the 

 respiratory organs, in nasal polypi, in tumors, in the faeces in helminthiasis, and 

 in the normal bone marrow. When the crystals are not present in the fresh 

 preparations, they form quickly if the blood, pus, bits of tissue, or other material 

 are preserved and kept from drying. The crystals can also be produced by the 

 action of various metallic salts upon the eosinophilic cells. 



The crystals can arise within the eosinphilic cells, and those that form out- 

 side the cells probably take their origin from eosinphilic granules, which lie 

 free in the tissue-spaces. It is not to be assumed that the eosinophilic granules 

 are directly transformed into crystals or simply supply the material by a 

 chemical change. Lewy advances the hypothesis that the mother-substance of 

 the crystals is formed physiologically in different tissues and is destroyed by the 

 round cells attracted thither by chemotaxis. Under certain conditions the mother- 

 substance is formed in such a large amount that a residue remains from which 

 the crystals arise. The eosinophilic granules are formed from this mother-sub- 

 stance by the action of the round cells, which become transformed into 

 eosinophiles. Lewy himself, however, brings forward objections to this 

 hypothesis. j. h. p. 



Glinski, L. K. Zur Kenntniss des Neben- A firm, oval, reddish gray, sharply cir- 



pankreas und verwandter Zustande. cumscribed body, 4.5 cm. long, was 

 Virchow s Archiv, lo4 : 132-145, 1901. _ _ •' ° 



discovered in the wall of the stomach 



near the pyloric end. It produced a bulging of the overlying mucous membrane 



into the cavity of the stomach. On microscopical examination the structure was 



recognized as an accessory pancreas. It was embedded in the muscular coat. 



In all the other recorded cases the accessory pancreas has been situated in the 



submucosa or between the serosa and the muscular layer. The author collected 



from the literature thirteen cases in which an accessory pancreas has been found. 



Three times it was located in the stomach wall; ten times in the wall of the 



intestine. The pancreas in some of the lower vertebrates is situated in the wall 



of the stomach or intestine, hence the accessory pancreas in man is regarded 



as a reversion to the original type. j. h. p. 



Warthin, A. S. A Contribution to the Normal Haemolymph nodes differ from ordi- 



Histology and Pathology of the Haemo- , , j • ^1 ^ ^1 



lymph Glands. Journal of the Boston "^ry lymph nodes m that they contam 



Society of Medical Sciences, 5: 416-436, blood-sinuses in place of the lymph- 



^ * sinuses. These bodies were discovered 



by Gibbes in 1889. Six years later they were described in more detail by Robert- 



