and Laboratory Methods. 1421 



material and for dissection, has long been a desideratum. This need is most 

 adequately met by Reighard and Jennings' work. The book is based upon a 

 decade of practical experience in anatomical instruction in the University of 

 Michigan and elsewhere, and is thus well adapted to the demands of university 

 courses, while at the same time affording a valuable guide to the private student 

 of anatomy and a desirable adjunct to the high school library. In symmetry of 

 treatment, in freedom from extraneous matter, in clearness, comprehensiveness, 

 and at the same time brevity of statement, and in technical execution, the book 

 may well serve as a model. Mrs. Jennings' accurate figures supplement the 

 text in all important subjects. 



The book contains adequate directions for the preparation of the various sys- 

 tems of organs and advocates the use of formalin as a preservative. A 5 per 

 cent, solution of commercial formalin is injected into the femoral artery to the 

 amount of 300 to 400 cubic centimeters. Specimens thus injected may be pre- 

 served thereafter by immersion in 1 per cent, formalin. Color and pliability 

 are better preserved by the following method : Inject 5 per cent formalin to 

 which has been added one-sixth of its volume of glycerin and keep the 

 specimen in a tight box, wrapping all exposed parts in cloths wet in the injecting 

 fluid. The suggestion is made that the addition of fungicides to the injecting 

 fluid might prevent the growth of molds which soon attack exposed surfaces. 



c. A. K. 



NORMAL AND PATHOLOGICAL HISTOLOGY. 



Joseph H. Pratt. 



Harvard University Medical School, Boston, Mass., to whom all books and 

 papers on these subjects should be sent for review. 



,.,,,, , ,. , This is a consideration of the general 



Pappenheim, A. Ueber das Vorkommen ein- ° 



kerniger Zellen ein gonorrhoischen Ure- histology of inflammation, and it pre- 

 thralsecret. Virchow's Archiv fur path. ^^^^^ ^^ admirable survey of recent 

 Anat., 164: 72-119, 1901. . . , . 



work in this field. The author dissents 



from the view of the Cohnheim school and adopts in modified form the original 



view of Virchow that the fixed cells of the part, as well as the extravasated cells 



from the blood, participate in the formation of pus. The polynuclear leucocytes 



are haematogenous in origin, but the lymphocytes and mononuclear leucocytes 



he regards as formed locally from the cells of the connective tissue group. 



Mononuclear cells occur in the gonorrhoeal discharge in all stages of the 



disease and they are always present in larger proportion, in relation to the poly- 



nuclears, in the exudate than in the blood. The lymphocytes are not simply the 



small typical lymphocytes of the blood ; many are of larger size, and forms as 



large as the great lymphocytes of acute lymphsemia are not uncommon. The 



mononuclear cells are found in the pus in clumps. As the process becomes 



more chronic there is a considerable increase of mononuclear leucocytes and 



particularly of lymphocytes. These facts favor the histogenetic origin of the 



