ABSTRACTS 127 



conclusion is drawn that complement plays no part in the anaphylactic 

 reaction and therefore that anaphylatoxin plays no role in this phe- 

 nomenon. — W. J. M. 



On the Mechanism of Anaphylaxis and Antianaphylaxis. J. Bronfen- 

 Brenner. Proc. Soc. Exp. Biol, and Med., 1915, 13, 19-21. 

 The author regards anaphylaxis as due to toxic split products of the 

 normal serum proteins produced by the action of the normal tryptic 

 ferment of the blood after the inhibitory influence of the colloids has 

 been diminished by the specific interaction of antigen and antibody. 

 Antianaphylaxis is explained as the result of antitryptic influence of 

 split products of products of proteolysis. — W. J. M. 



Agglutination of Bacteria in vivo; Its Relation to the Destruction of Bac- 

 teria Within the Infected Host and to Septicaemia. C. F. Bull. Proc. 

 Soc. Biol., and Med., 1915, 13, 32-33. 



Intravenous injection of immune serum causes an abrupt clumping 

 of bacteria in the circulating blood in bacteremia and their accumu- 

 lation in the internal organs, where they are phagocyted. — W. J. M. 



The Utilization of '^Reactor" Milk in Tuberculo-medicine. C. B. Fitz- 

 PATRicK. Proc. Soc. Biol, and Med., 1915, 13, 35-37. 

 Cows in excellent physical condition, but reacting to tuberculin, 

 were used. Seven patients with moderately advanced pulmonary 

 tuberculosis were fed upon their milk and showed improvement as 

 compared with control cases on normal milk. — W. J. M. 



Late Results in Active Immunization with Diphtheria Toxin- Antitoxin 



and with Toxin- Antitoxin Combined with Diphtheria Bacilli. W. H. 



Park and Abraham Zingher. Proc. N. Y. Path. Soc, 1915, N. S. 



16, 110-116. 



Individuals giving a negative Schick test before treatment are prob- 

 ably immune for life. Those who give a positive Schick test and who 

 have been exposed to diphtheria should receive either antitoxin alone or, 

 for longer protection, both antitoxin and toxin-antitoxin injections. For 

 general prophylaxis against diphtheria, not including immediate con- 

 tacts, toxin-antitoxin alone, or with the addition of killed diphtheria 

 bacilli, is recommended. The dose is 1 cc. of toxin-antitoxin (85 to 

 90 per cent of the L+ dose of toxin to each unit of antitoxin) and 1,000,- 

 000,000 bacteria, injected subcutaneously three times at intervals of 

 six or seven days. The early and the late results should be controlled 

 by the Schick test, early results within four weeks and late results from 

 four months to two years after the immunizing injection. — W. J. M. 



Agglutination in Pertussis. O. R. Povitzky ai^d E. Worth. Arch. 



Int. Med. 1916, 17, 279-292. 



The Bordet-Gengou bacillus, grown upon coagulated horse blood 

 veal agar, is readily agglutinated by immune serum. An agglutinating 



