700 ABSTRACTS 



pig. The results following the intravenous injection of this salt 

 ("cyanocuprol") are summarized as follows: The effect of a single 

 injection upon the lesions is either negative or inconspicuous. But 

 after repeated injections of the preparation the congestion and 

 leucocytic infiltration about the lesions are markedly decreased, the 

 cheesy material resulting from degeneration of the lesions and other 

 degeneration products are in process of absorption, and young connec- 

 tive tissue is being actively produced in the periphery. While these 

 changes are taking place the number of bacilli is also being reduced 

 until finally they can no longer be detected on microscopic examina- 

 tion. Whether the preparation brings about these results directly by 

 kilHng the bacilli or indirectly by favoring the healing process of the 

 body, it has power to inhibit the growth of or annihilate entirely the 

 bacilli in vitro. — B. W. 



A Contribution to the Chemotherapy of Tuberculosis. First Clinical Re- 

 port. G. KoGA. Jour. Exp. Med., 1916, 24, 149-186. 

 The author concludes, from a study of sixty-three cases, that cyano- 

 cuprol given intravenouoly to tuberculous individuals, greatly improves 

 or apparently cures pulmonary and surgical tuberculosis in the first 

 and second stage, and it seems also to produce beneficial effects upon 

 the disease in the third stage. The duration of these beneficial effects 

 is still to be established. — B. W. 



The Treatment of Tuberculosis with Cyanocuprol. M. Otani. Jour. 



Exp. Med., 1916, 2, 187-206. 



The paper deals with the clinical treatment of tuberculous patients 

 with ''cyanocuprol." The author claims marked efficacy for the treat- 

 ment and gives directions for dosage, intervals for injection, precau- 

 tions and contraindications. — B. W. 



The Treatment of Leprosy with Cyanocuprol. R. Takano. Jour. Exp. 



Med., 1916, 24, 207-211. 



A brief report of treatment of leprosy with cyanocuprol which 

 appears to be attended with beneficial results. — B. W. 



Elective Localization of Bacteria in Diseases of the Nervous System. E. 



C. RosENow. Jour. A. M. A., 1916, 67, 662-665. 



A study of the possible etiologic relationship of focal infection to 

 diseases of the nervous system. 



Three strains of organisms, one staphylococcus and two green- 

 producing streptococci, isolated from tonsils or teeth in cases of mul- 

 tiple sclerosis produced lesions of the spinal cord in 58 per cent of the 

 animals inoculated. 



A staphylococcus was isolated from a typical case of sporadic ante- 

 rior poliomyelitis, which caused lesions of the spinal cord in 78 per cent 

 of the animals injected. 



