COMPARISON OF LOEFFLER'S COAGULATED BLOOD 



SERUM AND BLOOD SERUM WITH THE 



ADDITION OF STERILE OX GALL 



HELEN R. ODELL 



New York State Department of Health, Albany, New York 

 Received for publication September 17, 1917 



In 1913 Von Drigalski and Bierast reported on the results 

 obtained by the comparative use of Loeffler's original coagulated 

 blood serum plate medium and blood serum medium with the 

 addition of sterile ox gall, in the isolation of the diphtheria 

 bacilli. Drigalski' s medium was prepared according to the 

 original formula with the addition of 0.13 parts ox gall. They 

 concluded from their work that the modified Loeffler medium 

 rendered the isolation of diphtheria bacilli more certain and 

 in many cases easier, due to the increase in the number of diph- 

 theria colonies on the plates. 



Biising in 1914 repeated the work and compiled the results of 

 various other workers in the use of Drigalski's serum medium. 

 The following table shows the results collected by Busing. 



Table of results 



Drigalski and Bierast, 1913 



"Halle" 



Seligman 



Voelckel, 1913 



Schulz, 1913 



Grundmann, 1913 



Busing, 1913 



POSITIVE ON 

 BOTH MEDIA 



36 

 81 

 30 

 35 

 8 

 70 

 79 



POSITIVE ON 



DRIQALSEI 

 MEDIA ONLT 



17 



17 

 9 

 

 

 

 2 



POSITIVE ON 



LOEFFLER 

 MEDIA ONLT 





 

 3 

 4 

 2 

 20 

 7 



There were 384 positive findings with Drigalski's medium 

 and 375 with Loeffler's medium, showing in 420 examinations 



189 



