126 C. C. WARDEN, J. T. CONNELL AND L, E. HOLLY 



has been brought out in the paper of Connell and Holly ''On 

 the Nature of Hemolysin." 



We believe there has been adduced fair evidence warranting 

 the following tentative conclusions: 



1. The C. diphtheriae and B. megatherium possess character- 

 istic fat complexes which are, under proper colloidal conditions, 

 the true antigens of these microorganisms. Artificial fat anti- 

 gens have replaced the antigens of the germ bodies in the various 

 immune reactions. 



2. The lysins and toxins of the C. diphtheriae and the B. 

 megatherium are the same substances, being, respectively, the 

 specific fat antigens of the microorganisms existing in definite 

 and particular colloidal states. 



3. Aside from colloidal or emulsifying activity cellular protein 

 appears to have no place in the immune reactions studied. 



