o F !•: V I-; u . 



ilruys, tlu- circulation can bo excited much beyond tlie point that it reaches in fever, 

 but under these circumstances tlic elevation of temperature never approaches that 

 of hij^h fever. 



Disturbani-fs of imtritKni, iiuliuliiip: secretion and excretion, arc certainly capable 

 of causing; fever, but that such disturl^anees are not ahvjiys tlie cause of the febrile 

 state is shown by the circumstance that fever may be {generated in the normal 

 animal by external heat without a previous appreciable alteration of secretion or 

 nutrition. It would indeed appear that derangement of nutritive functions ia 

 tVequcntly a secondary and not a primary phenomenon of fever. 



I'rom the considi'ratioiis just bntught forward it would appear that sudi dis- 

 orders of circulation, innervation, or nutrition as constitute the gross symptoms of 

 fever are not essential to fever, /. c, capable of i)roducing the other phenomena of 

 the febrile state, an<l that if any one fever symptom be tlie cause of the otlier fever 

 symptoms, it must be the elevated temperature. 



NN'hen we desire to heat any inorganic body wc do it by applying to it heat, 

 but the living animal body has power of resisting the absorption of heat by means 

 60 well known as not to require consideration here. This power is, however, limited, 

 and wc are able to heat the animal provided tiic external warmth be sufficient and 

 be applied with sufficient persistency. 



The following series of experiments was performed to determine the effect of 

 heating the animal body. In the first two trials natural heat was employed. A 

 box was constructed rudely with a slanting glass lid, like a miniature green-hou.se. 

 It was simply placed upon a brick pavement, when used, in such a way that the 

 sun could exert its fullest power upon it. In the other experiments arliticial heat 

 was employed. 



EXI'EUIME.NT 1. 



Exposed a Iwo-lliinls-prown rnUbit in n box covered witli pluss. 



1 p. M. — Toinporaturp in rectum, 104°. 5 F. Tc'n)i>er(iltirc of \)i>\, 120^ F. 



1:15 p. M. — Temperature, lOfi'^.S. Ue-spirntion very hurried. 



1::50 P.M. — Temperature, 109'. 5. llao convulsive attacks, in which he jumps, and kicks with 

 bind leRs wilh great fury. 



1:45 P. M. — Temperature, 112'. Seems very weak and rela.\cd ; breathing 220 a minute. Lies 

 on side, wilh every now and then tlie attack.s alluded to; slobbering greatly. 



2:10 p. M. — Temperature of Imjx, 120°. Rabbit on side, exceedingly weak, ga.s|iing; stiueaiing 

 faintly at intervals. 



2:15 p M. — Temperature, 114°.5. Perfectly onconscious; lies relaxcil and motionless on the cool 

 gnniiid in the xhade. 



2:20 P.M. — Only ga-iiping at long intervals; heart still beating, although luboreilly, and fome- 

 what irrrgnlBrly. yet pretty steadily, and with some force. 



2:21 p. M.— Dead. 



Aulnpity. — Heart: right nide and left onride full of blood; left ."side containing blood, not ron- 

 trnrte*!. The heart made a few very imperfect and feeble attempts at Ix'aling when it woji cut 

 across. Hlond coagulating with great rapidity and (irmne.«s; alkaline. Ilrain not congested. 

 M ' failing to show the tilifrhtesit sign of contraction under the strongest faradic current, 



c^ , ' "'' the leg muscles, which contracted very feebly, and only when the curritii was vcr>' 



fnlens' 



