98 ^' ': V 10 R. 



ArTKii Injection. 



Fftll o( animal Ivmpcraturo in 1 j hours S.-'iH, in 1 hoar 4.18& — t. 



Q — \V X I X »|>. h. — 30 X 4.1M5 X 0.7r» .= 112.995 — hcnl lost from rwcrvc. 

 Iliiiirly diiuipation i>r heat TllMM 



Hourly luiis from heal rt-scrvc 11^.995 



SUVMABT 



Hourly production of heat 10K.3C0C 



Hourly prodnclion of heat l)oforc injection 2.'i".l904 

 Hourly production of heat aflcr injection 106.3C06 



Diminution of hourly production of heat /allowing injection 148.8298 



These expcrinu-nts do not require cxtonded coninient. Tlio first would srcm to 

 indicate that in the dofj the corpus striatum is connected either directly or hy cou- 

 ductiun with the function of heat production. The small size of the dojj and the 

 consequently minute amount of heat dissipated increases, however, f,'reatly the 

 chances of error, and not very much confidence can he put in tlie sinyle experiment. 



The great diminution of heat production which foUowetl the operation in the 

 second experiment was jjrobably due to shock, *. c, vaso-motor palsy, caused by 

 the destruction of nearly a whole cerebral hemisphere. 



Tlie only conclusion to be dniwn is that the method employed is a doubtful one, 

 and that no decided ligiit has been thus far thrown upon the position of the inhibi- 

 lory heat centre by its employment. 



Eulenburg and Landois reported in VirclKUc's Archiv, Bd. Ixviii., p. 245. a series 

 of experiments upon the effect of destruction of the cerebral cortex on the tempera- 

 ture of the feet of do;^s. They found that when a certain region in the neighbor- 

 hood of the sulcus cruciatus was destroyed either by means of a hot iron or by 

 chemical reagents, almost immediately the temperature of the opposite extremities 

 rose. They assert that in some cases the difference between the feet of the two side* 

 amounted to 1:}° C. (2:3°.4 F.), and that occasionally it wiis oidy 1°.5 C. (2^.7 V.). 

 They located the exact position of this region as iuing bonb red anteriorly by the 

 sulcus cruciatus, and extending to the fourth primitive convolution embracing 

 especially a " hackenformig" gyrus which appears to correspond to the gyrus 

 postfrontalis (Owen) in man and apes. They also state that they were able to 

 separate the region presiding over the front from that governing the hinder ex- 

 tremities, the focus for the front legs lying somewhat more forward and in imme- 

 diate proximity to the distal end of the sulcus cruciatus. Eulenburg nnd 

 Landois further discovered that when tlie region was irritated with a galvanic 

 current the paws grew cooler. The duration of the elevation of temperature after 

 destruction of the cerebral temperature varied. In most cases the increased 

 warmth was perceptilile for a long time, in some instances for three months; but 

 in some dogs it disappeared after two or three days. Other portions of the cere- 

 bral surface than those already spoken of were destroyed without perceptible 

 thermic effect. 



This research of Landois and Kulenburg is in accord with that of Trof K. 

 Ilitzig (Cn/i-iilhhitt /iir die Mol. WisHnsvh., ISTt), p. 323), so that the main fnrfs 

 must be considered as almost established. Led by these corroborated stutenieiits 



