A STUDY IN MORBID AND NORMAL PUYSIOLOGY 



2od 



RECAPITULATION. 



Time. He.yt He.vt Reot. Temp. 



DijMl'ATloN. Pkouiitios. (Fall.) 



First d'ly f 8:40 p. m. to 12:10 a. .m. 18.01 I7.h5f;3 l03O.(i to 103^.4 



June 5, 8:30 P. .Ni. to I l^^"*-^-'" «:Wa..m. 5.8304* 5.4205* 1U2 to 101.2 



Juue 0,8:30 P.M. ] ^■^^^■^■'- ^^■"^''■^- 2--^-«l-'« 23.1347 lUO.w to 101.8 



I 4 p. .«. to 8 1-. .M. 17.4025 17.4025 lOl.G to lOl.O 



June 7. 11 a.m. — Ten miuiius o! putrid Ijloud injected into the jugular vein. 

 June 8. 10.30 a.m. — Five uiuiii.is ol jjutnd blood iiijeetcd into llie jugular veiu. 

 2:40 p, M. — Five miuiius of putrid blood injected into tlie jugular vein. 



Remarks. 



The experiments whirli have just heen recorded, al'liongh undertaken for the 

 purpose of determining whether there is or is not a greater production of heat in 

 fever tlian in healtli, are capable of throwing hglit upon other problems, and it 

 seems best to examine one or two of these before discussing the main question. 

 There are two inquiries concerning the production of heat in health which may 

 well here be studied. First, as to the existence or non-existence of a regular diur- 

 nal cycle of change in tlie lieat production corresponding to the diurnal vtiriations 

 of bodily temperature. Second, as to the effect of food upon heat production. 01 

 the experiments capable of throwing light upon the second of tlicse inquiries 

 No. 110 affords two days for comparison: the first of these days the dog ate one 

 pound of raw liver when entering the calorimeter; the second he was without food. 

 During the first day his average hourly heat production was 105.-145; during the 

 second day it was 61.4198 units; furtlier, during the five liours immediately after 

 the ingestion of the liver it was 170.8262, whilst during tlie second day the highest 

 hourlf production reached was 8i).2437. The next experiuu>nt bearing directly 

 upon the point now at issue is No. 1 1 4. During tlie first (hty the dog ate at intervals 

 considerably over a pound and a half of meat, whilst on the second day he fasted ; 

 the result being that the average hourly heat production was the first day 84.2426, 

 the second day 60.156 units. Tiie decisive results obtained in tliese two experi- 

 ments are confirmed by tlie immediate effects of the administration of food in one 

 or two of the other experiments. They are also in accord with tiie results obtained 

 by Senator, so that it may be considered demonstrated that tlie ingestion of a large 

 amount of animal food is usually followed by an enormous increase in tlie pro- 



* There was evidently some mistake made in reading the calorimetrical thermometer in this run, 

 henee in makinp; averan:e it is omitted. 



30 October, 1880. 



