A STUDY IN MORBID AND NORMAL PHYSIOLOWY, 



2'.ib 



pendent upon the relations of heat dissipation to heat production rather tlian upon 

 any dominant alteration of heat production. It is perhaps going too far to assume 

 at present tiiat what is true of the dog must also be true of the man. hut the pro- 

 babilities are that in this respect there is no difference between tlie two, for my 

 experience seems to show that there is in dogs as well as man sufferin«>- from 

 pytemia an evening rise of temperature. 



C^oming now to the main question — the one for whose answering the present 

 series of experiments were especially undertaken— 1 find the evidence of six of the 

 experiments is best displayed by [)lacing the results iu tabular form as follows. 

 The seventh experiment di tiers from the others in that it did not extend ov(>r 

 several days, and its results therefore cannot be thrown into the same table with 

 those of the others. The headings of the table explain sufficiently its purport 

 without further comment. 



Food Day. HrsGER Day. First Fever Day. Second Fever Day. 



Aver.'ige Averai;e Hours Average Averajre Hours Average Average Hours Averase Average Hours 



No. of Rectal Hourly Heat in Kectal Hourly Heat in Rectal Hourly Heat in Rectal Hourly Heat in 



Exp. Temp. Production. Box. Temp. Production. Box. Tem|>. Production. Box. Temp. Production. Box. 

 (Fah.) (Fah.) (Fah.) (Fah.) 



110 102.39 105.445 15 102.83 G1.4198 17 103.02 87.4777 15 105.42 02.82.52 15 



111 104.07 139.4733 17 104.78* 128.0702 17 104.89 130.1177 15 105.39 133.250 20 



112 19.25 103.4 G8.()59 19.25 104.2 f.2.9151 IG 105.08 75 85C6 21 



113 102.0 97.4839 17.25 103.7 94 3229 14.5 105 115.5817 15 



114 102.24 84.2420 20 101.4 60.15G 18 102.4 97.7511 17.5 



net 101.6 19.4955 13 104.2 22.2755 19 



To this table must be added the results obtained in experiment 115 for a single day. 

 On studying the table it will be seen that in Experiment 1 10 the production of animal 

 heat during each fever day was much greater than during the day of abstinence, 

 but less than when food was taken, also that the heat production during the fever 

 rose with the average daily temperature. In Experiment 111 the day marked 

 hunger day w^is one of feeding ; under these circumstances there was a decline in 

 the production of heat during the fever, but no proper comparison can be made 

 between the fever day and a hunger day. It will be noticed that the heat pro- 

 duction was less than when the dog was bountifully fed in health. Experiment 

 112 conformed in its results with Experiment 110; as did also Experiment 

 113, excepting that there was a diminished heat production during the first day 

 of tlie fever. In Experiment 114, during what is marked as "second fever day" 

 there was a production of animal lunit much exceeding even that of feeding day, 

 although the average temperature of the animal was very little above normal. Ihe 

 animal was at the time fatally sick, refusing food and dying within forty-eight hours. 



A very curious fact is demonstrated by this experiment. If the fever process be 

 considered to be that ultimate disorder of nutrition which produces the excessive 



* The dog had i pound of raw liv.r this day. It was not, therefore, really a hunircr day; there 

 was also elevation of temperature following an injection of pus, so that the day should be perhaps 

 considered as a "fever day."' 



t A rabbit allowed to eat all it wouhl. 



