ojo ii; villi. 



A inuiliTuti* ^izt■<J niulv cat 



KXTKUIMKNT IIH. 



UK.MAIiK.S. 



Iliiir n flitiildrai-lim of |iu8 icijcctcd into the cellular tUiue. 

 A Uuii|.Ururliiii iiiji-ctcd. 



Opoiird tlic linen alba niid IrntifiriTrcd the thcrmumctcr to the pcrlton<-«l 



cavity. 

 Slrun;; curn-iit a|i|iliud to thu fcuural ucrvu. 

 Current broken. 



Current reapplied. 

 Curreiil brukeu. 



TliermonietPr rctransfcrrcd to the rccfom. 

 Cut killed. 



The rrsiilts i»f tliesc experiments are at seeming variance with those of R. 

 Ilcidenhain (/^/(V;/e/-'« Archie, lid. 111. \>. .>lf>). Tliat observer failed to get a fall 

 of teminratiirc in fever following galvanic irritation of a nerve. The difference 

 liriil);ibly deiMiiils npon the use by IJeidenhain of feeble currents whilst those 

 cniployed by myself were very powerful. The experiments just recorded are con- 

 hnned by other evidence. A comparison of tlie result ])rodnced in my experi- 

 ments by section of the medulla at the pons upon heat jtroduction with tho.sc 

 obtained in tlic exi)erimcnts on heat production in fever will show that in iiyjcniic 

 fevrr there cannot be a complete palsy of th(> inhibitory centre. Tlic increase of 

 tissue; change in fever is not sufficient for comjjlete paralysis. 



This does not at all show that what increase of chemical movements there is, is 

 not due to a ])artial loss of power of the inhibitory heat centre. The existence of 

 such partial loss of |)ower woidd bring into accord the experiments of Ilcidenhain 

 and myself. Thus it is c(inceiv;d)le that he (Miijjloying feeble currents, just suffi- 

 cient to influence a normal centre, failed to affi-ct the jjaretic centre of the fevered 

 nuimal; whilst I, using very ])owerful currents, succeeded in arousing the centre, 

 although partially benumbed by the pya-mic poison. 



To tletermine more accurately the condition of the inhibitory heat centres in 

 Iixamic fever the following experiments were jierfornied. 'i"h(> ear was the jiart 

 idways irritated, and the same l)u Hois lieymond coil and galvanic cell were 

 employed so as to give uniform intensity of irritation. 



