A STUDY OF FEVER. 29 



Remarks. 

 Arterial pressure 120 ; on galvanizing nerve it fell at 

 first but soon rose to 185, no movements except in 

 muscles supplied by nerve were elicited. 



Dog put in a box at temperature 90°. 

 Temperature of box 102°. 

 .104. 

 90. 



" 88. 



94. 

 " 84. 



82. 



76. 

 " " 72. 



64. 



" 64. 



64. 



Next morning the dog was found dead. 



Autopsy — Medulla was nearly severed obliquel}^, where it 

 merged into the pons. 



In this experiment you see a fall of temperature preceded the 

 rise, which was apparently due to the dog's being placed in a 

 hot box. The cause of this fall I cannot completely establish; 

 certainly, however, the fever, when developed, was indepen- 

 dent of the external heat, for whilst the latter was steadily fall- 

 ing from 104° to 72°, the animal heat rose from 104° to 107°. 

 In this experiment the arterial pressure rose from 120 to 185, 

 when a sensitive nerve was galvanized, and the vaso-motor sys- 

 tem was therefore intact. The fact that the medulla oblongata 

 was not completely divided probably accounts for the want of as 

 rapid a rise of temperature in this as in the previous experi- 

 ments ; if there be a " fever centre," the separation of it from 

 the rest of the body was not complete but partial, and, there- 

 fore, it was not to be expected that the rise of animal heat would 

 be as rapid or intense as in the previous experiments. What- 



