REPARATORY IXFLAMIMATIOX IX ARTERIES. 7 



the human subject, and the practice of torsion was introtluccd 

 and published to the worhl. 



Blandin (Journal Ilebdomadaire, mai 1830) accepted the 

 organization of the thrombus, and its thorough adhesion to 

 the vessel walls, and Alannec (Traite Theorique et Pratique de 

 la Ligature des Arteres, 1832) was in accord with this view; 

 on the other hand, Walther (S\-steme de Chirurgie, 1833) and 

 M. Lobstein (Pathologische Anatomic, 1834) were of the 0})po- 

 site opinion. 



W. B. Costello, a foriner pupil of M. Amusat, followed the 

 communication of his master b^^ a paper read before the West- 

 minster Medical Society on " Torsion of Arteries for the pur- 

 pose of Arresting Hemorrhage" (London Lancet, March 8, 

 1834), in which experiments upon dogs were detailed. 



Stilling (Ueber Bildnngund Metamorphose des Thrombus in 

 verletzten Blutgefasen, Eisenach, 1834) repeated and corrobo- 

 rated the researches of Petit. He saw the adhesion of the clot 

 to the wall of the vessel, its pyramidal shape, considered 

 eighteen hours as about the length of time requisite for its 

 formation, and admitted, with Moran, the action of the liga- 

 ture on the two iuner tunics of tlie vessel. 



Pirogoff (Ueber die Durchshneidung der Achillessehne. 

 Dorpat, 1840) defended the general proposition that fibrin 

 possesses a power of self-organization. 



Zwicky (Metamorphose des Thrombus, 1845) recognized 

 fibrin as a formative element in the process of organization. 

 For him fibrin forms a plastic exudation upon the inner wall 

 of the vessel, and effects the growth of the latter to tlw 

 thrombus. The fibrin found in the thrombus as one of its 

 elements likewise soon organizes itself there. He observed 

 the formation of vessels in the thrombus. 



Both Castelnau and Notta (De la cicatrisation des ailcres. 

 Gazette des Hopitaux, 1851, No. 13, 14) confessed to the same 



