8 THE TONER LECTURES. 



opinion, and claimed further that the thrombus is subject to 

 purulent degeneration. 



Thierfelder (De regeneratione tendinum, 1852) is to be 

 ranged with Pirogoff and the others who admit the formative 

 power of fibrin. 



Henry Lee (On the deposition of fibrin in the lining mem- 

 brane of veins. Med.-Chir. Transactions, 1852) did not think 

 that in Gendrin's experiments sufficient care had been taken to 

 exclude the possible presence of a small blood-clot. He devised 

 a method by which this dilemma could be avoided, and he 

 aspired to put the question of the role of the vessel wall at 

 rest forever by performing a solitary experiment. This author 

 concluded that the blood coagulum is necessary to the pres- 

 ence of inflammation, and that it acts as a foreign body, the 

 inflammation excited bj' it being a natural process for its elim- 

 ination. This inflammation begins in the outer, and thence 

 extends to the inner coat; extends to the lining membrane of 

 the vein, and not from it. 



Boner (Die Regeneration der Sehnen. Yirchow's Arch., 1854) 

 acquiesced in the independent formative power of the fibrin 

 wherever found. 



Rokitansky (Pathologische Anatomic, 1856) regarded the 

 walls of the vessel as the origin of the material which finally 

 fills the lumen and becomes organized. 



Meckel (Microgeologie, Herausgegeben von Billroth, 1856) 

 was among the first in this connection who began to perceive in 

 the white blood-corpuscle an element wdiich might possess capa- 

 bilities that should not be entirely overlooked in the examina- 

 tion of these processes. However, he neither ascribed to the 

 leucocyte any great role, nor yet denied to it a power of 

 organization. 



Virchow (Canstatt Jahresbericht, Bd. 1, I. 31) advanced the 

 opinion that the white blood-corpuscle as a formative element 

 carries the fibrin. 



