10 THE TONER LECTURES. 



Klin. Woclienschrift, 18G4) made a series of experiments upon 

 dogs and rabbits, directed to the determination of the mode of 

 vascularization of the thrombus. He concluded from his numer- 

 ous observations : — 



1st. That the red corpuscles and the fibrin degenerate and 

 disappear. 



2d. That the white cells by means of their peculiar move- 

 ments during the first hours undergo a change into bodies of a 

 peculiar shape, and very soon become transformed into spindle- 

 form cells. 



3d. That in the first four days the extremities of the prolon- 

 gations are seen uniting and forming a network, taking position 

 in lines having every semblance of vessels. 



4th. That the 3'ounger vessels are generally formed in the 

 periphery of the thrombus. 



5th. That by the end of the third or fourth week, the vessels 

 of the thrombus have formed a union with those of the adven- 

 titia. At the place of ligature where the intima and media are 

 lacerated, the vessels of the adventitia pass directly into the 

 throml)us ; farther away from the ligature, they reach the 

 thrombus by penetrating the intima. 



Gth. That b}' the fiftieth to the sixtieth day the whole throm- 

 bus, especially its periphery, is full of bloodvessels. A single 

 large one is often seen in the centre. 



Hh. That these vessels subsequently close up, 



Forster (Handl)uch der Patholog. Anatomic, 1865) denied 

 the organization of the thrombus, and believed that the healing 

 and final obliteration of the veins are due to a growth of the 

 walls. 



Strieker (IJeber das Leben der favblosen Blutkorperchen. 

 Sitzungs-berichte der Akademie der Wissenschaften, 1867) 

 admitted the viability of the Mdiite corpuscle in the thrombus, 

 but did not affirm its formative power. 



Obolensky (Ueber die Organisation dc« Blutes. Protokoll 



