S4 THE TONER LECTURES. 



The above observations were several times repeated, usuallj' 

 with the same result. They left in my mind but little doubt 

 that the three lower i)ortions of the clot of 48 hours, and the 

 same appearance of the other blood coagula found in my prepa- 

 rations, were produced in a similar manner. 



The ditferent portions of the clot of 48 hours were bound 

 together rather firmly by intercrossing bands of fibrin in the 

 same manner, altliough not so tiglitly, as the previously' men- 

 tioned juxtaposed bands of the serpentine lamella were united. 

 The coagulum was found to be more adherent to one side of 

 the vessel than to the other. This union also was effected by 

 bands of fibrin, similar to the preceding. 



We now come to another remarkable feature in the construc- 

 tion of this particular thrombus, which, so far as my observa- 

 tion has gone, is only to be seen occasionall3\ Tlie fourth por- 

 tion — that which formed the apex of the thrombus — had a con- 

 stitution different from that of the preceding. It appeared to 

 be composed of three distinct laj'^ers, separately superim[)Osed. 

 Furthermore, each layer corresponded in homogeneity of struc- 

 ture to the description which Billrotli and Rindfleisch have 

 given of the whole of the recently formed thrombus. They 

 were, so to speak, homogeneous throughout — no massing of red 

 or white corpuscles anywhere, not the slightest appearance of 

 stratification. Moreover, there were to be remarked through- 

 out the separate coagula constituting this portion of tlie 

 thrombus a small number of flat OA'oid cells with clear contents, 

 the nucleus slightly oval, and the quantit^^ of protoplasm large 

 in proportion to the size of the nucleus. The long diameter of 

 these cells was often three or four times that of the neighboring 

 white blood-corpuscles. These flat cells were more numerous 

 in the superior la3'er, and more scarce in the lower stratum. 

 Besides this difference in the strata composing this upper por- 

 tion, it was also to be noted that the lowest was the largest, 



