40 THE TONER LECTURES. 



some of the intertrabecnlar spaces. Frequently, however, 

 considerable masses of decolorized red disks can be seen filling 

 out the spaces, while the trabeculse are stained and infiltrated 

 with numerous colored granules. 



Fig. 7. Vascularized tissue obliterating the lumen of a 

 femoral artery of a dog twenty-one days after ligature, injected 

 with Beale's blue, low power, a. Adventitia. m. Media, p. 

 Vascularized granulation-tissue, the dark lines in which repre- 

 sent bloodvessels which are seen to be in communication above 

 with the open lumen (L) of the artery, v. Varix in the cellu- 

 lar new formation below the point of ligature, the same being 

 developed from the vasa vasorum. p, v. Similar varix in the 

 bottom of the plastic clot. The two varices communicate by 

 means of small capillaries passing between breaks in tlie elas- 

 tic laj'er (e) of the intima. i. Thickened intima. This thick- 

 ening extends up to the first collateral branch. 



In otlier and a little older preparations, the communication 

 between the varices was accomplished by one or two tolerably 

 large trunks. 



Fig. 8. Longitudinal section of the femoral arter}- of a dog 

 twenty-five days after ligature, injected. Low power, a. Ad- 

 ventitia. m. Media, m'. Media at end of arter^^ where ligature 

 was applied, c. Cellular tissue, e. Elastic layer of intima at 

 side of artery, wliere it appears unbroken and unchanged. /. 

 Thickened cellular portion of intima, on a level with blood-clot. 

 V. Varices in the cellular tissue at end of the arter3% T. Large 

 trunk which establislies the anastomosis of external vessels 

 with those of the clot. A few smaller vessels jjass directly 

 from the varices to the capillaries at the sides of the plastic 

 formation obstructing the lumen, p. Thoroughly vascularized 

 plastic clot, now showing commencing cavernous transforma- 

 tion. Up the centre of this is seen to pass a large vascular 

 stem. 



It is observable, both in this figure and in the one imme- 



