42 THE TOXER LECTURES. 



to the neighborhood of the elastic layer of the intiraa, were a 

 number of cells similar to those previously described as gener- 

 ally present after the ordinary application of the ligature, but 

 neither the leucocytes nor the epithelioid cells seemed to be 

 possessed of any great degree of activit}-. The media and 

 adventitia in this neighborhood were the seat of a very lively 

 cellular infiltration. The lower blood-clot appeared \ery com- 

 pletely to fill out that portion of the calibre of the artery in 

 which it was located. The most striking phenomena were ob- 

 served at the level of the point of compression by the forceps. 

 At this point there were very decided indications of a lively 

 state of activity in the intima and innermost layers of the 

 media. At the point of compression, and in a decreasing 

 degree a little above and below it, an accumulation upon the 

 intima of the same kiud of cells which constituted the pre- 

 viously described plastic clot of 24 hours, was very noticeable. 

 In longitudinal section, this accumulation, having its greatest 

 deptli at the point of compression, formed a considerable prom- 

 ontory which projected from each side into the lumen. The 

 elastic layer of the intima at this point was more deeply 

 stained with carmine than were the portions more remote. It 

 was also to be noticed that the elastic la^'er in this situation 

 ■was slightly bulged inward b}^ a tumefaction and a cellular 

 infiltration of tlie inner layers of the media. This cellular 

 infiltration of the inner layers of the media was limited to the 

 inner lamellae, and was not even here decided. Tliere was no 

 decided increase of protoplasmic elements, either in the exter- 

 nal layers of the media, or in the adventitia. Nor was there 

 any other appearance leading to an inference that there liad 

 been anj^ wandering of white blood-corpuscles from the vasa 

 vasorura. 



Sections from the preparations eight and ten daj^s old 

 showed only a further advance of tlie same process. The 

 two opposite promontories projecting into the lumen whc^e 



