QUININ. 117 



timony, and 3 pts. vegetable charcoal. This mixture is to be 

 heated in a covered crucible, and when the fluid mass ceases 

 to foam, it is to be boiled in a capsule with 1 pt* sulphur and 

 q. s. of distilled water. The liquor, filtered and left to repose, 

 deposits colorless crystals of SNaS + SbSj+lSHC. (Repert. 

 der Pharm. 1848, and Chem. Gaz. vi. 268.) 



Black Sulplmret of Mercury. — Vogler (Journ. de Pharm. 

 1848) prepares this salt more. readily than by trituration, as 

 follows. 4 oz. mercury are mixed with 1 oz. sublimed sulphur, 

 washed and sieved, and the whole placed in a capacious glass 

 vessel, and shaken for two hours. After this, another ounce 

 of sulphur is added at intervals, and the agitation continued 

 until every trace of mercury ceases to be visible to the eye. 

 Two more ounces of sulphur are then added, and the mix- 

 ture again shaken until the entire incorporation of the mer- 

 cury with the sulphur, as may be ascertained by the aid of 

 a lens. 



2. Organic Bodies. — Some of the most interesting of these, 

 to the pharmaceutist, are the alkaloids, and the volatile liquids 

 chloroform and collodion. 



Separation of Cinclionin from Quinin. — 0. Henry's process 

 (Journ. de Pharm. 1849) for determining the proportion of 

 cinchonin in sulphate of quinin is based upon the difference in 

 solubility, in cold water, of the acetates of the two alkaloids. 

 10 grm. of the mixed sulphates are mixed with 4 grm. acetate 

 baryta, triturated with 60 grm. water, slightly acidulated with 

 acetic acid, strained and filtered. Two volumes of alcohol of 

 35° are added to the filtrate, and then sulphuric acid in ex- 

 cess. After filtration, add ammonia, and boil : the cinchonin 

 precipitates while the quinin remains in the alcoholic liquid. 



Quinidin. — This new alkaloid, according to F. L. Winck- 

 ler (Buch. Rep. xlviii. 385), occurs, with quinin, in one of the 

 new barks most resembling Huamalies. It is crystallizable, 

 soluble in alcohol, and slightly so in water. Its sulphate is so 

 similar in appearance to the sulphate of quinin, that it is diffi- 

 cultly distinguishable from the former. 



Quinoidin. — After preparing quinin and cinchonin from 



