ACETO ACETIC ESTER 97 



Alcoholic ammonia acts on it to form a body C7 H15 N3 O3 , which 



/ NHCONH2 

 may be represented thus : — CH3 C / NH2 and which is 



~^CHC-OH 



\ OC. H5 

 /9-uramidocrotonic amid together with one molecule of alcohol. 

 Boiling this with water decomposes it into urea, acetone, alcohol, car- 

 bon dioxid and ammonia. 



MEWES, W., 1888. 



Ann. Chem. 245, 58-84 ; J. Chem. Soc. 54i 817 ; Ber. 21, 473 (C). 



Halogen Substitution Products of Acetoacetic Ester 



and their Behavior with Sodethoxid. 



Passing chlorin through acetoacetic ester produces the mono-, di-, 

 tri- and tetra-chlor-acetoacetic esters which boil at 194°, 205°-207°, 223°- 

 225°, and 245°-250° respectively. Some difficulty was found in entirely 

 separating them from one another. The bromo-chlor-acetoacetic esters 

 were formed by treating the chlor-acetoacetic esters with bromin and 

 also by treating the bromo-acetoacetic esters with chlorin. Sodethoxid 

 decomposes all of the halogen derivatives forming the mono- or di- 

 halogen acetic esters. Bromoacetoacetic ester with sodethoxid yields 

 succinosuccinic ester. When the chlorobrom-substitution products are 

 treated with sodethoxid, sodium brotnid is always formed. 



KNORR, L., 1888. 



Ann. Chem. 245, 357-382 ; J. Chem Soc. 54. mi ; Ber. 21, 628 (C). 



Synthetical Researches on Acetoacetic Ester. Part IV. 



Methyl-acetoacetic anilid, CH3COCH (CH3) CONHCeHj , which was 

 prepared from methyl-acetoacetic ester and anilin, melts at 138° to 140^ 

 Sulfuric acid changes it into dimethyl-carbostyril [3': 4'], a weak acid 

 from which the dimethyl product Cg H4 OH (CH3)2 N was obtained. 

 Chlor-dimethyl-quinolin [CI : (CH3)2=2':3':4'], ortho- [4': i], meta- and 

 para- [4' : 3] dimethyl-quinolin were described together with some phenyl, 

 nitrogenous derivatives. 



