240 



KIYOSHI MASÜI. 



Eiiscliista=5. He says : " lu the six-rmatjcj-te they (plasmosomes) arise iu cluse 

 coutact with the unclear meiubraue, and at the same time in connection with 

 the end of the autosome, wliich would suggest thi^t the plasmosome is either 

 the joint product of chromatin and cytoplasm, or else represents snljstance 

 taken up by the nucleus from the cj-toplasm." 



IV. The Growth of the Chromatin Spireme. 



In the prophase of the primary siDerumtocyte, together with the gi-owth of 

 the cell the chromatin S])ii-eraes grow considerably. At this stage they lu-e 

 st:iined faintly with iron-hsematoxylin, while their affinity for acid-fuchsLu 

 gradnally increases. A careful observation shows that this change of the stain- 

 ing capacity is due to the accumulation of the achromatic substance within 

 tlu! cla'omatin spkemes. 



Tliis change of the staining capacity proceeds with the gro%\'th of 

 the cell body as well as tLat of the nucleus, until the bulk of the cell 

 attains its greatest size. In the metaphjise of the fii'st reduction division 

 the achi'omatic substance of the chromosome entirely disappears, and the 

 cliromosomes are stainal deeply with methyl-green with Auerbach's method. 

 From these facts it is most probable that the achromatic substance of the 

 chromosome is used up for the chi-omatius in the prophase. A similar pheno- 

 menon has already been described by Bonnevie ('08). He says: "Während 

 nach dem obigen das Waclistum der Chromosomen in einer Zunahme ihrer 

 Chromatinsuljstanz Ijesteht, scheint die während der Prophase erfolgende 

 Volumziuiiihme in einer diurch Flüssigkeitaufnahme eingeleiteten Neubildung 

 achi'omatischer Substanz zu bestehen, und zwar so, dass ihre Menge von der 

 Grösse jedes Chromatinfadens Ixjstimmt wird." 



Moreover as to the sti-uctui'e of the clu'omosome his interpretation is as 

 follows : " Die neu gebildete acliromatische Substanz scheint durch eine innei-e 

 Differenzierung der Chromosomen iu ilirer IVIitte augesammelt und von einer 

 ol)erfläclil:ch gelegenen Schicht clu-omatischtr Suljsfcmz umgelieu zii werden." 



Y. The Mitochondria. 



The lx)liavior of the mitcwhondrial granules iu the mouse and the rabbit 

 is, except in some jwiuts, cntirelj' similar to tliat described by Düesberg ('11) 



