and Laboratory Methods. 2151 



GENERAL PHYSIOLOGY. 



RAYMOND PEARL, University of Michigan. 



Books and Papers for Review should be Sent to Raymond Pearl, Zoological Laboratory, 

 University of Michigan, Ann Arbor, Mich. 



Lohmann, A. Untersuchungen iiber die Ver- The author suggests as a useful substi- 

 weithbarkeit eines Delphininpraparates an ^ . , , 



Stelle des Curare in der Muskelphysiologis- t"te for curare in work on muscle- 

 chen Technik. Arch. f. d. ges. Physiol. 92 : physiology an easily soluble preparation 

 473 47 , 1902. ^^ delphiniii, made by G. Heyl in Darm- 



stadt. The curare preparations on the market are rather uncertain in their 

 action, and pure curarin is too expensive for general use, so that a reliable inex- 

 pensive substitute for curare is much to be desired. As the result of a series of 

 comparative test experiments Lohmann thinks such a substitute is afforded in 

 delphinin. One gram of delphinin to 1000 gr. of frog produces complete paraly- 

 sis as a rule. The poison is injected subcutaneously in 4 to 8 percent, solution. 

 In about one minute the frog becomes sufficiently paralyzed so that it will remain 

 quiet in any position, although direct stimulation of a nerve will still cause mus- 

 cular spasms. Experiments showed that the delphinin had no effect on the 

 form of the contractions, nor was the magnitude of the contractions of the pois- 

 oned muscle less than in the case of the normal muscle. Detailed descriptions 

 of the action of the drug are given in the paper. The preparation of delphinin 

 recommended may be obtained from E. Merck, Darmstadt. R. p. 



c«,„<.ii r. IT 1 ^- r. Ml An extensive, detailed study by means 



rorsell, u. Ueber die Bewegungen in Hand- '^" ^ > j .j 



gelenk des Menschen. Skand. Arch. f. of Rontgen rays of the movements of 



Physiol. 12 : 168-358. Taf. v-viii, 190.. ^^^ ^^^^^ ^^ ^^^ ^^^ig^_ P^H directions 



for the use of this method for studying the movements of joints are given. 



R. p. 



Kuliabko, A. Studien uber die Wiederbele- % "^^ans of an artificial circulation of 



bung des Herzens. Arch. f. d. ges. Physiol. Locke's solution, warmed to body tem- 



90: 46:-47i, Taf 111,1902. perature, through the isolated heart, 



Neue Versuche liber die Wieder- '■ 11 u • 



belebung des Herzens. Wiederbelebung Kuliabko has been able tO obtam extra- 



des menschlichen Herzens. Centralbl. f. ordinary results in causing a renewal 



Physiol. 16: 3-50-^^1, 1002. -^ . ,. , ^ 



of activity m the mammalian heart 



after its apparent death, and at considerable intervals of time after the death of 

 the animal. As an example of his results an experiment described in the earlier 

 of the two papers may be mentioned. The heart of a rabbit was removed and 

 an artificial circulation of Locke's solution at a temperature of 40°C. was kept 

 up through it for about an hour. The heart beat regularly and strongly during 

 this time. At the end of the hour the current of fluid was stopped and the 

 heart with the attached cannula was placed in an ice-chest where the tempera- 

 ture was practically 0°C. In five minutes all pulsation had ceased. After the 

 heart had remained on the ice for 18 hours it was removed and again connected 

 with the circulation apparatus. In less than a half minute after the circulation 



