2152 Journal of Applied Microscopy 



began, strong, rhythmical contractions in the region of the openings of the vense 

 cava; appeared. This pulsation soon spread till it included all the heart except 

 the left ventricle, which in this particular experiment did not regain its activity. 

 A number of experiments similar to this are described in detail, and an excel- 

 lent review of the literature of the subject is given. 



In the second of the papers the author reports a continuation of these experi- 

 ments. He has been able to bring about, by the same method as that used in 

 the. earlier experiments, a re-appearance of pulsations in rabbit and bird hearts 

 after periods of total inactivity of as long as three, four and even five days. 

 These results were obtained not only with hearts removed from freshly killed, 

 healthy animals, but also with hearts from animals which had died natural deaths 

 (from disease or otherwise). This led to a series of experiments with hearts 

 from human bodies. The heart of a boy who had died of ptieinnonia duplex was 

 removed from the body about twenty hours after death, taken to the laboratory 

 and flushed through the aorta with warm, oxygenated Locke's solution. In 

 about twenty minutes parts of the heart began to pulsate and finally the move- 

 ment extended over the whole organ, and the whole heart continued to beat reg- 

 ularly for an hour. The same results were obtained in numerous experiments 

 with the human heart, not reported in detail in this prelirninary communication. 

 The author points out the evident practical importance of these results in cases 

 of stopping of the heart beat and apparent death. r. p. 



NORMAL AND PATHOLOGICAL HISTOLOGY. 



JOSEPH H. PRATT, Harvard University Medical School. 



Books for Review and Separates of Papers on these Subjects should be Sent to Joseph H. Pratt, 

 Harvard University Medical School, Boston, Mass. 



Moak. On the Occurrence of Carcinoma and j^Jq^^ presents five cases in which 

 tuberculosis in the Same Organ or tissue. '■ 



The J. of Med. Research, 8: 128-147, 1902. carcinoma and tuberculosis were 



found associated in the same organ 

 or tissue. He found carcinoma might be the primary process and the tuber- 

 culosis secondary. In one case he observed quiescent tuberculosis of a gland 

 which was secondarily invaded by metastatic carcinoma. In another both 

 diseases seemed to be transmitted in the same way as metastases, and at the same 

 time. He concludes, then, that either may appear first or both may be noted at 

 the same time. The difference in the form of combination depends partly on 

 the anatomical peculiarities and partly on the susceptibility of the tissue to one 

 or the other of the diseases. In considering the supposed antagonism, he states 

 that the following points should be borne in mind : 1. Cases of active tubercu- 

 losis occur, for the most part, at a time of life before cancer becomes prevalent- 

 '2. If latent or healed tuberculosis be taken into account it is evident that the two 

 diseases must be very frequently associated in the same individual. 3. The 

 organs most frequently affected by tuberculosis are not the organs most frequently 

 attacked by carcinoma. He is of the opinion that no real antagonism exists. 



w. R. s. 



