7 o 



Journal of Agricultural Research 



Vol. XX, No. i 



than three days. The autopsies were negative. No evidence of an 

 intercurrent disease was obtained. 



The results of this series of experiments are given in Table I. 



TABLE I. — Results of experiments with echinacea in the treatment of tetanus 



6 (con- 

 trols). 



Effect. 



Tetanus. . 

 ....do... 

 ....do... 

 ....do... 



...do... 



...do... 



...do... 

 ...do... 

 ....do... 

 ....do... 

 ....do... 

 ...do... 

 ....do... 

 ....do... 

 ....do... 

 ....do... 

 ....do... 

 ....do... 



...do... 

 ....do... 

 ....do... 



...do... 

 ....do... 



...do... 

 ...do... 

 ....do... 

 ....do... 

 ....do... 

 ...do... 



Termination. 



Died. 



Number of days 

 sick. 



.do 2. 



.do 2. 



.do j 2. 



.do Less than 3. 



do. 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do... 

 ..do.. 

 ..do.., 

 ..do.., 



Do. 

 Do. 

 Do. 

 Do. 



Less than 3. 

 Do. 

 Do. 



2. 



" Minimal lethal dose. 

 SUMMARY OF EXPERIMENTS WITH TETANUS 



"Specific Medicine Echinacea" was administered to guinea pigs both 

 per os and intramuscularly, the "Subculoyd Inula and Echinacea" was 

 administered to guinea pigs intramuscularly, and 69 per cent alcohol was 

 injected intramuscularly into guinea pigs, as a means of treatment for 

 tetanus. All of these animals were injected with 3 minimal lethal doses 

 of standard tetanus toxin in solution, some animals being injected sev- 

 eral days after they had been treated with echinacea, while others were 

 injected first and then treated with echinacea. Neither the protective 

 treatment nor the remedial treatment nor a combination of the two 

 appeared to influence the course of the disease, as all the experimental 

 animals acted in the same way and died in the same time as the controls. 

 From these results it does not appear that echinacea possesses remedial 

 value against experimental tetanus in laboratory animals. 



