Oct. i, 1920 An Experimental Study of Echinacea Therapy 83 



GENERAL SUMMARY 



Various preparations of echinacea — namely, the "Specific Medicine 

 Echinacea," the fluid extract echinacea, and the "Subculoyd Inula and 

 Echinacea" — were studied as remedies in several types of infectious and 

 allied diseases, both acute and chronic, in guinea pigs. 



In both tetanus and botulism produced by the administration of 

 bacterial toxin the course of the disease was not modified by the echinacea. 



In septicemia produced by injection of a culture of Bacillus bovi- 

 septicus, and in anthrax produced by injection of B. anthracis the 

 results indicated that echinacea had no influence. 



In poisoning by the venin of the rattlesnake produced by injection 

 of a solution of the dry venom the echinacea preparations were without 

 curative effect. 



In the chronic diseases, tuberculosis produced by injection of a 

 human strain of the bacillus and trypanosomiasis produced by injec- 

 tion of Trypanosoma equiperdum the remedy was exhibited over an 

 extended period of time without apparently influencing the course of 

 these diseases. 



Definite evidence of organic effects from the echinacea itself was not 



obtained. 



LITERATURE CITED 



(1) American Pharmaceutical Association. 



1918. THE national Formulary, ed. 4, 394 p. Philadelphia. 



(2) Berg, W. N., and KelsEr, R. A. 



1918. DESTRUCTION OF TETANUS ANTITOXIN BY CHEMICAL AGENTS. In JoUT. 



Agr. Research, v. 13, no. 10, p. 471-495, 4 fig. Literature cited, p. 

 cited, p. 494-495- 



(3) Council on Pharmacy and Chemistry. 



1909. echinacea considered valueless, report of the council on phar- 

 macy and chemistry. In Jour. Amer. Med. Assoc, v. 53, no. 22, p. 

 1836. 



(4) Ellingwood, Finley. 



1914. echinacea: the vegetable "antitoxin." its characteristics and 

 peculiar therapeutic effects. In Amer. Jour. Clin. Med., v. 21, 

 no. 11, p. 987-993. 



(5) Fish, P. A. 



1903. echinacea in veterinary practice. In Amer. Vet. Rev., v. 27, no. 8, 

 p. 716-726, 1 fig. 



(6) Gray, Asa. 



[1908.] new manual of botany . . . ed. 7, 926 p., illus. New York. 



(7) Heyl, Frederick W., and Hart, Merrill C. 



1915. some constituents of the root of brauneria ANGusTrFOLiA. In Jour. 

 Amer. Chem. Soc, v. 37, no. 7, p. 1769-1778. 



(8) and Staley, J. F. 



1914. analyses OF Two echinacea roots. In Amer. Jour. Pharrn., v. 86, 

 no. 10, p. 45°-455- 



(9) KrLGOUR, J. C. 



1897. lobelia and echinacea. In Eclectic Med. Jour., v. 57, no. 11, p. 

 595-598. 



