Nov. IS. 191S Gossypol, the Toxic Substance in Cottonseed Meal 287 



(7) Methods for rendering cottonseed kernels nontoxic depend upon 

 extracting the gossypol or changing it to physiologically inert forms by 

 oxidation or by precipitation. 



(8) The smallest amount of gossypol administered intraperitoneally 

 by us and found fatal to rabbits was 0.24 gm. of crystalline gossypol 

 acetate per kilo of live weight. 



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