MOSQUITOES 75 



malarial season was on. The house stood near the banks 

 of a canal in which was an abundance of the larvae of 

 Anopheles. They went out during the day ; at times 

 allowed themselves to become wet to the skin ; left the 

 windows open at night so that the bad air could enter and 

 circulate all through the house ; in fact, they did every- 

 thing that an ordinary inhabitant would do, with one 

 exception ; namely, they went into the house before six 

 o'clock every day and so evaded being bitten by Anopheles 

 mosquitoes. It must also be mentioned that they took 

 no quinine or other preventive medicines against malaria. 

 It was said that the critical test would come when the 

 rainy season began in the autumn. At this time, the 

 people living under ordinary conditions suffered much 

 from chills and fever. But through it all, these two phy- 

 sicians developed not the remotest trace of chills or fever. 

 It was certainly a remarkable and triumphant vindication 

 of the labors and conclusions of Laveran, Ross, Celli, and 

 many others. But this is not all. There yet lacked one 

 more link in this chain of evidence. The chain had been 

 surely forged link by link during all these years since 1880 

 through the persistent and brilliant researches of the men 

 mentioned above and now came the forging of the last 

 link that vindicated their wisdom. 



A son of the renowned Manson, at that time living in 

 London and who had not been in a malarious country 

 since childhood and was therefore as free from the disease 

 as one could well be, offered himself as a subject for the 

 forging of this last link. Bastianelli, the famous Italian 

 whom we have mentioned before, procured some Anopheles 

 mosquitoes and turned them loose upon a man in Rome 

 suffering from malaria. They, of course, bit the man many 



