CINCHONA. ORD. XIV. Rubiacez. $1 
gents, but not gelatine; the second precipitates gelatine, but not astringents ; 
the third precipitates both gelatine and astringents; and lastly, there are 
some barks which precipitate neither gelatine nor astringents: but these he 
did not consider as properly belonging to the genus cinchona, Each of the 
three first classes was thought capable of curing intermittents, 
It had been long a desideratum among pharmaceutical chemists to dis- 
cover in the barks the particular substance to which the febrifuge property 
might be ascribed; and in pursuit of this object, MM. Laubert of Paris, 
Strenss of Moscow, and Gomez of Lisbon, published, about the same time, 
the result of their observation ; unfortunately, however, they did not agree 
in their conclusions.. The French chemists were more successful; they ob- 
tained a substance, which they recognized as that to which M. Gomez had 
given the name of cinchonine, and they further discovered that it was an al- 
kaline. 
The cinchonine was obtained by operating on the cinchona nd nc sat 
or Grey-bark of the French botanists. The cinchona cordifolia, (the cinchona 
officinalis of our Colleges, the yellow-bark of the French), was next subjected 
to analysis,t and from this was obtained an alkali, in many points resembling 
the cinchonine, but still differing in many important ones, sufficiently to pre- 
vent their being confounded : this new alkali was called Quinine. The ex- 
amination of the red-bark (cinchona oblongifolia) followed ;{ and “it was an 
interesting question,” says M. Magendie, “to determine whether this species, 
* According to the analysis of MM. Caventou and Pelletier, the Cinchona Conda- 
minea yield the following constituents :—1! cinchonine united with Kinic acid (the cin- 
chonine forming 0 ,2 per cent. of the whole bark); 2 green fatty matter ; 3 red colouring 
matter, very sparingly gages 3 4 red colouring matter, soluble (tannin); 5 yellow co- 
louring matter ; 6 Kinate of lime; 7 gum ; 8 fecula; and 9 ligneous fibre. 
+ The Cinchona ee yielded, according to M. M. Pelletier and Caventou :— 
1 yellow, odorous, adipocire ; 2 yellow colouring matter ; 3 tannin, which turns iron of 
a green colour; 4 red of cinchona, more abundant than in the red bark; 5 Kinate of 
quinine, with very little einchonine (the quinine forming 0,9 per cent. of the bark, but 
according to Voreton, 1,4); 6 fecula; 7 woody fibre ; and 8 Kinate of lime. 
t The Cinchona oblongifolia consists of :—1 adipocire; 2 yellow colouring matter 
3 aces 4 red of cinchona, in a large proportion ; 5, Kinates of cinchonine and quinine 
_ (100 parts of the bark, yielding 0,8 of cinchonine, and 1,7 of sinbiias 6 fecula; 7 
woody fibre ; 8 Kinate of lime. Magendie, Formulaire. 4 
