CINCHONA. ORD. XIV. Rubiacez. 35 
paration of which the rods of the electroscope are susceptible : the electricity 
was always vitreous. The sulphate of cinchonine possesses the same phos- 
phorescent property, but in a less degree, and the electric faculty in the same 
ration ¥ oe Ss . : 
The Medical Properties and Uses of Peruvian Bark will be found under 
the article cinchona officinalis, in Vol. IL. of this Work. We have, therefore, 
only to notice in this place the medical properties and formularies for the 
exhibition of the cinchonine and quinine. M. Magendie says—‘“A sufficient 
number of cases induce me to believe that these two alkalies (cinchonine 
and quinine) possess the medical properties of the cinchonas, and may be 
substituted for them on all occasions.” In the twelfth volume of the Medi- 
co-Chirurgical Transactions, Dr. Elliotson has sufficiently established. the 
febrifuge efficacy of both simple quinine, and of the sulphate, which is fur- 
ther confirmed by Dr. Dickson of Clifton, in the Edinburgh Medical and 
Surgical Journal for October 1823. But indeed it is needless now to insist 
upon the value of these preparations; since, in the ague counties of Eng- 
“and, their use is become general, and seldom fails to effect a cure. As a 
general tonic, both the cinchonine-and. quinine may be successfully exhibited, 
in all cases wherein the cinchona would be indicated. M. Magendie says— 
“The sulphates are the preparations most commonly employed ;” and he 
recommends “from one to eight grains to be given in the twenty-four hours.t 
Some physicians,” he adds, “have thought it necessary to carry the dose 
much higher, but in general the result has not answered their expectations, 
and several patients have experienced severe symptoms, such as great agita- 
tion, with strong cerebral excitement."t) 0 = 
Cinchoniné is thought to possess the febrifuge properties in a less degree 
than quinine; ‘the sulphate of the latter is the preparation now generally 
employed in England, and the following seems to be the best mode of exhi- 
biting it. Dissolve the sulphate in a little lemon-juice, and then add a suf- 
ficient quantity of pure water, or of cinnamon or peppermint water, to make 
a draught. In this way two grains may be given for a dose, and repeated 
three or four times a day. The following formularies for the exhibition of 
* Appendix to Formulary, by R. Dunglison, p. 25, 
+ According to Paris, eight grains of the sulphate is equal to one oz. of bark. 
+ In large doses it often occasions severe nausea. 
F 2 
