on. 2 ae RANGNOULACE A, 
“as the  Sardonic grin,” It is called ‘in English, Wat 
Crowfoot and Celery-leaved Crowfoot, and in Arahics, Kaf-és 
saba. (Cf. Dios. IT., 166 ; Pliny 25, 109.) 
Remarks.—Galen tells us that the Anemones are emmena> 
gogie and galactagogue, and have acrid, drawing, cleansin 
and opening ,properties; when chewed they increase 
" secretion. of saliva. The juice cleanses- the brain wl 
administered by the nostrils, and lessens or removes opaci 
of. the cornéa; it cleanses ulcers and cures scaly skin dise 
aft ‘applied. focally, &c. In Europe the drug appears to ha 
when Stork again brought it to notice, and latterly,in Ame 
several Species of Anemone, under the name of Pulsatilla an 
- their active principle anemonin, have been rather extravaga 
praised as remedies for a long. list of diseases. When pt 
- anemonin-is given to rabbits in doses of from 5 to 10 grains, 
reduces the -pulse, and respiration. rate and the temperature 
causes dyspnoea and stertor; debility, and then paralysis o 
limbs, stupor, dilatation followed by contraction of the pupil, 
death without convulsions. - On dissection, the heart and 
vessels and the veins of the brain and medulla are foun 
tended with dark blood. (Clarius. ) Externally it acts. 
irritant to the skin. The extract and. tincture of the’ 
differ’ from pure anemonin, inasmuch as. large doses ca 3 
inflammation of the stomach and bowels and death with. con- 
vulsions. The cause of this difference has not been ascertained. 
; Applied to the tongue, both the drug and anemonin cause 
sense of burning followed by numbness. In medicinal do 
. (4 to 5 grains of the herb or} to} a grain of anemonin)™ 
‘drug is now considered to act asa general ae 
diuretic. 
The different species of tit and Reowseabee whe 
: distilled with water yield a distillate, from which ~ 
extracts a very acrid yellow oil (anefnonol) which is: grad 
+ or more rapidly in the presence: of water, conve: 
__ anemonin and anemonic acid, from which hot + aleohol 
