‘pregnant female, but when once parturition has commence 
180 | RUBIACE&. : 
‘Quinine has no power to originate uterine contractions in 
the flagging pains are greatly stimulated and increased b 
dose of ten grains of the drug, and when abortion is threa 
through malarial influence, no hesitation should be felt in 
it. Quinine should always be given in some easily sola 
form, as any salt of the alkaloid which escapes absorption 
hours previous to the last. -When there is sufficient time, its 
influence is almost always very sensibly aided by the e 
tion, 12 or more hours before, of a mercurial or other p 
In typhus and typhoid fever, scarlatina, severe erysi 
rheumatic hyperesia, &c., after the use of the cold bath, 
grains are often very efficacious in preventing a rapid ret 
of the excessive fever. (U.S. Dispensatory, 1889.) 
In the year 1866, the Madras Government appointed a 
cal Commission to test the respective effiacy in the treatm 
fever of quinine, quinidine, cinchonine and cinchonidix 
From the Report it appears that the number of 
paroxysmal malarious fevers treated was 2,4.72,—nam: 
with quinine, 664 with quinidine, 559 with cinchonine 
403 with cinchonidine. Of these 2,472 cases, 2,445 were cl 
and 27 failed. The difference in remedial value of the 
alkaloids as deduced from these experiments may be 
Quinidine—ratio of failure per 1000 ......... 
ining.) 2s hea eee te erg en ae 
ee 
