TOGANTACR®. = =——— sigs 
contraction and-.by. rendering. the «chest immovable, that. it” 
tends to produce asphyxia, with its: usual symptoms;of dark 
venous -congestion of the eyes and interior,of the..mouth. 
This explanation renders clear the agency of artificial. ‘Tespira- 
tion in saving. the life of. animals in strychnine-poisoning 
(Richet, Med. News, etc., Nov. 1880, p. 659), and the effect, of 
) 'strychiine has been eliminated.” (Nutional Dispensatory. ) 
Strychnine is generally supposed to have no action upon: 
the brain, but E. Biernaki (Ther. Mntsh. Aug. 1890) from. 
experiments made upon rabbits under the influence of chloro. . 
form found that the excitability of the cortical portion of the 
brain, showed a diminution in from 8 to 10 minutes after the: 
inistration of strychnine, this diminution of excitability. 
reached its maximum in from 27 to 30 minutes, then remained 
onary for a time (according : to the dose given) after which 5 
passu, with the diminution of sensibility, in the ‘cortical : 
ion of the brain, as excitation of one portion of the oo 
ous system is known to produce a » depressing action —, . 
her Chae 
r diseases i in which there is hyperexcitability of the brain. 
regards the treatment. of ‘strychnine poisoning, ‘as 
+hshould” be evacuated-and ® brisk purgative adminis- 
