LA BIA T^. 121 



r 



T 



also examined. One of these, wliich he had crystallized from 

 cold alcohol, melted at 153-5° to 154-5° C, was evidently nearly 

 pure ; the average of three combustions gave : — 



C 70-54 



H 



O, 



9-08 



20-38 



100-00 



The otlier samples ^yere evidently the same compound in an 

 impurer condition, as was found by combustion and melting 



m 



point. The author here remarks ; 



'*This compound as well as that obtained by myself is 



4 



evidently the marrubiin discovered by Mein in 1855. Harm 

 {Archiv der Pharmacie, No. 83, p. 14i) stated the meltiug point 

 to be 148^0. 



^*In a later commimication (No. 116, page 41), on elementary 

 analysis he found the substance to contain 8*52 per cent- of 

 hydrogen and more than 69 per cent, of carbon,. 



■ n 



" Kromayer [Archiv der Fharmaciey No. 108, p. 257) gives 

 the yield of marrubiin as about 2 grams from 25 pounds of the 

 drug, and states the melting point to be about 160*^G., and 

 that it is not a glucoside. My results indicate its composition 

 to be very close to that of absinthiin, O^^H^^O^ but they do not 

 agree with all the properties of that substance as described by 

 Kromayer in the same journal (No. 108, p. 20), who states 

 that absinthiin melts at 120'^to 125° C. Many of the properties, 

 however, are common to both substances, prominent amonof 

 which are, — solubility, taste, grittiness between the teeth, 

 crystalline appearance and percentage composition/^ 



The larger portion of the drug, after exhaustion with ether, 

 was extracted with methyl alcohol, the solvent recovered, and 

 the residue treated with water and filtered. 



* - . , _ 



The filtrate, on agitation successively with ether and chloro- 

 form, yielded to the former a^ ve-i-y hitter greenish substance 



111.-16 



