VBTICACEjE. 327 



bring about toxic effects in the majority of healthy adults ; and 

 i of a grain has done the same, but never J^, which is the 



m 



grown persons, j\ of a grain being the proper initial dose for 

 children. The best preparation for administration is the 

 tincture— 1 grain to 20 or 10 minims —dropped on sugar or 



bread. 



given 



repeated every four or six hours and gradually increased every 

 third or fourth day, until either relief is obtained or the drug 

 is proved useless. With such precautions, Dr. Eeynolds 

 states he has never met with toxic effects, and rarely failed to 

 ascertain in a short space of time the value or uselessness of the 



drug 



Its most important results are to be found in the mental 

 sphere ; as, for instance, in Senile Insomnia, with wandering. 

 An elderly person (perhaps with brain softening), is fidgety at 

 night, goes to bed, gets up, thinks he has some appointment to 

 keep, that he must dress and go out. Day, with its stimuli 

 and real occupations, finds him quite rational again. Nothing 

 can compare in utility to a moderate dose of Indian hemp at 

 bedtime — ^ to ^ of a grain of the extract. In alcoholic sub- 



tain 



Melancholia 



inverting 



but unless the case has merged into senile degeneration. 

 Dr. Reynolds does not now employ cannabis indica. It is worse 



In the occasional night 



mama 



restlessness of general paretics and of sufferers from the 

 *' temper disease " of Marshall Hall; whether children or adults, 

 it has proved eminently useful. 



In painful affections, such as Neuralgia, Neuritis, and 

 Migraine, Dr. Reynolds considers hemp by far the most useful 

 of drugs, even when the disease is of years' duration. In 

 neuritis the remedy is useful only in conjunction with other 

 treatment, and is a most valuable adjunct to mercury, iodine, 

 or other drugs, as it is in neuralgia when given with arsenic, 



quimne 



Many victims 



