APPENDIX, IGS 



quantity for laboratory experiments. These experiments showed 

 that any of the crystalline bodies would prevent the growth of the 

 tubercle bacillus if present in the proportion of 1 in 10,000, and in 

 any ordinary cultivating medium for this bacillus. The effect of 

 the administration of the alantic anhydride appeared to be to pro- 

 long life for a time in the animals experimented on, but not to 

 prevent a fatal result, Helenin has also been lately given with good 

 results in leucorrhoea in the dose of 2-4 centigrammes {Rep. ds 

 Fhar7H., Oct., p, 481). {Pharyn. Journ,, Oct. 31, 1891.) 



Plucliea lanceolata. 



Description.— Shrubby, hoary pubescent, with sessile, very coria- 

 ccous, oblong or oblanceolate entire leaves, one to two inches in 

 length, having strong very oblique nerves on both surfaces. When 

 dry, the leaves are of a pale yellowish -green. Heads of flowers in 

 compound corymbs about the siae of Groundsel, purple, involucre 

 bracts contracted at the mouth, outer bracts obtuse, hoary. The 

 drug has no marked tast^. 



Chemical composition.— The taste of these leaves is saltish and 

 aromatic. They yield, in an air-diied state, 16'93 per cent, of 

 mineral matter, consisting largely of alkaline chlorides, the cubical 

 crystals of which were deposited on inspissating the alcoholic and 

 aqueous extracts of the plant. Caoutchouc, and an organic-acid 

 giving a green precipitate with ferric salts, were present, but no 

 alkaloid. We have tried some experiments with preparations of 

 Pluchea leaves, and conclude that, weight for weight, they are much 

 weaker than senna leaves in their cathartic action. 



Mydriatic 



The attention of the author was drawn a few months ago to the 

 mydriatic action of an extract prepared at Illtchin from common 

 lettuce, Lactuca sativa, when in flower. On examination, the myd- 

 riatic action was found to be due to an alkaloid. The extract 

 closely resembled belladonna extract in appearance, smell, and taste ; 

 but a dose of 5 grains had been taken vnthout injurious effects. 

 Th.a. ^fT,.,, ...^^«r/.i'n1 Pxtracts of lettuce were, examined -namely, 



wild 



^^ _ _^ Jritish Pharmacopceia, the history of which was 



unknown", ind^itracts of both the wUd and the cultivated lettuce 



directions 



