464 



Observations on Inoculation ivith the Virus of 



The fluid having been selected, inoculation is performed by 

 making an incision about an inch or rather more in length in the 

 skin of the tail, three inches from its termination. Into this 

 incision about a drachm of the fluid may be poured ; the tail is 



Fig. 2. 



-Fluid from the cavitij of the chest of a Coiv affected itith 

 Pleura-Pneumonia, magnified 1300 diameters. 







held in a fixed position for a few moments, and then released, 

 when the greater part of the fluid escapes. Some operators prefer 

 to saturate cotton threads with the exudate and introduce them 

 beneath the skin of the tail in the form of a seton ; much less 

 fluid is thus introduced, and it might be supposed that the opera- 

 tion would be more safe than the ordinary one ; but it is certain 

 that the method of inoculation by incision does not produce too 

 positive results, and it is probable that so long as a careful 

 operator conducts the experiment, the precise manner of intro- 

 ducing the exudate into the system is a matter of indifference. 

 No immediate effects follow the operation of inoculation by 

 incision. The wound on the following day will be filled up with 

 coagulated blood, and there will be no more swelling ordinarily 

 than would have occurred if the part had been simply incised 

 and no morbid matter had been introduced. 



Plate I. represents the appearance which the inoculated part 

 presents for some time after the operation. At the end of a week 



