ON HETEROCHROMIA IRIDIS IN MAN AND 

 ANIMALS FROM THE GENETIC POINT OF 

 VIEW. 



By C. J. BOND, F.R.C.S. 



CONTENTS. 



PAGE 



Part I. Irregularity of eye colour pattern in Man and Animals .... 99 



In Man 102 



In Eabbits Ill 



In Pigeons 112 



In Cats 116 



Association between eye colour pattern and skin or coat colour 



pattern ........... 117 



Hair pattern in man 121 



Part II. Irregular eye colour pattern and the constitution of gametic factors . 122 



Bibliography 128 



PART I.. 



Irregularity of Eye Colour Pattern in Man and Animals. 



It has been known for a long time that iu a certain proportion of 

 the population the eyes of one and the same individual are of a different 

 colour sufficiently marked to attract attention. In earlier references to 

 heterochromia attention was chiefly directed to the frequent association 

 of this condition of unequal pigmentation of the iris with diseased 

 conditions, such as glaucoma, cataract, cyclitis, and corneal opacities, 

 generally in the lighter coloured eye. 



Thus Sir J. Hutchinson (1) in 1869 reported three cases with 

 imperfect vision in the blue eye. Marcus Gunn(2) and Sym(2a) 

 in 1889, and Malgat (3) note the association with cataract in the 

 lighter eye. 



