0. J. Bond 107 



One daughter K. F. has a black spot on a lighter duplex back- 

 ground on the lower half of the right iris, the left also being brown 

 duplex. 



Four children W. F., G. F., I. F. and Al. F. are dark brown self- 

 duplex, and one B. F. is a green self-duplex. 



The father I. F. has two sisters also with irregular iris pigmentation 

 of the ray-type. 



In the " D " family (Whitby), Fig. IV, the father is a heterozygous 

 ring-duplex of irregular pattern with excess of pigment in the upper 

 part of the ring; the mother is a heterozygous ring-duplex, and three 

 cases (Florence, Ethel, Kate) of ring- pattern heterochromia occur in a 

 family of ten children. 



In two other families (Martin and Cavanagh) familial facts occurred. 

 In one (Martin) a duplex ray in the child was associated with an 

 irregular dark patch in a ring-duplex in the father (Case 9, Fig. V 

 and Case 9, Fig. VI). In one (Cavanagh) a duplex ray in the mother 

 was associated with a dark patch in a ring-duplex in the son (Cases 22 

 and 23, Fig. V). 



The following diagrams will serve to illustrate the form the ray 

 pattern assumed, and the position the coloured sector occupied on the 

 iris in 24 cases, in which, with the exception of cases 9, 22 and 23, no 

 familial incidence was recorded. 



Irregular Type of the Ring Pattern. 



One case, a woman aet. 34, Mrs A. B. (Case 8, Fig. VI), was seen of 

 abnormal structure pattern apart from pigmentary abnormality in a 

 simplex eye. In both blue eyes an inner ring of dark blue immediately 

 surrounding the pupil was itself surrounded by a wider ring of light 

 blue reaching nearly to the periphery of the iris. This outer ring had 

 the dog-toothed margin and the radial striated appearance of the simplex 

 iris, the peculiar appearance of two concentric rings being due to the 

 outer zone of more opaque radial fibres round the inner ring of circular 

 transparent fibres. 



In Case 1 L. C. a broad brown ring surrounded the pupil in the 

 right eye and a narrow yellow ring the pupil of the left eye, giving an 

 appearance of heterochromia in the two eyes. 



In Case 5 (shown also as Case 12 in the ray-table) is a duplex ray 

 in an otherwise simplex right eye. This ray was associated with two 

 dark pigment patches on the lower half of the sclerotic. 



In one Case 6 N. H. the difference in area and degree of 



