1915] Kidney Response in Uranium ]^ephritis 139 



swelling is slight. Vacuolation of the cytoplasm which is 

 such a constant and marked feature in the epithelium of the 

 anuric group is rarely present. 



Henle's loop tubules, and especially the ascending limb of 

 Henle's loop contains a small amount of fat. 



The epithelial involvement in the diuretic animals 

 (Groups I and III) is most marked in those animals which 

 either have a comparatively slight flow of urine or that dur- 

 ing the course of the experiment become anuric (experiment 

 6, Group I, table 1; experiment 6, Group III, table 3). In 

 such animals the epithelium of the convoluted tubules shows 



Fig. 3 



The figure represents ihe kidney of an animal which remained 

 dieuretic following morphine-ether. The epithelium is not necrotic and 

 shows only a slight degree of swelling. The histological changes are 

 comparable to those changes seen in Figure 1. 



both swelling and vacuolation, while the epithelium of tu- 

 bules deep in the cortex occasionally show areas of necrosis. 

 Such areas are small and limited to a few tubules. 



In the anuric group of animals (Group II) the epithel- 

 ium becomes actuallv swollen and vacuolated and the swollen 



