W. J. V. OSTERHOUT 429 



SUMMARY. 



1. The equations which serve to predict the injury of tissue in 0.52 

 M NaCl and in 0.278 m CaCl2 and its subsequent recovery (when it is 

 replaced in sea water) also enable us to predict the behavior of tissue 

 in mixtures of these solutions, as well as its recovery in sea water after 

 exposure to mixtures. 



2. The reactions which are assumed in order to account for the be- 

 havior of the tissue proceed as if they were inhibited by a salt com- 

 pound formed by the union of NaCl and CaCl2 with some constituent 

 of the protoplasm (certain of these reactions are accelerated by 

 CaCla). 



3. In this and preceding papers a quantitative theory is developed 

 in order to explain: (a) the toxicity of NaCl and CaCl2; (b) the antagon- 

 ism between these substances ; (c) the fact that recovery (in sea water) 

 may be partial or complete, depending on the length of exposure to 

 the toxic solution. 



