102 



Journal of the Mitchell Society {^Decemher 



entire series of experiments, it must be fully appreciated that 

 such tabulations of statistics are wholly inadequate to present 

 many features of the experiments that are equally as important 

 as those thus presented, and attention will be especially directed 

 to such features. Further, as can be seen from these tables, it 

 has been the object of the author to study effects in individual 

 animals with a variety of doses, as occasion suggested, rather 

 than to mould all the experiments to a single type or plan, for 

 it became evident early in this investigation that individual 

 peculiarities of the animals played a prominent role in the re- 

 sults obtained. 



Without exception, every dose of hematin administered has 

 elicited a definite temperature response. With but three excep- 

 tions, this response has been characterized by a sharp rise in 

 temperature, reaching the fastigium in about an hour and a 



Text-Fig. 2. The usual types of temperature curve following injections 



of hematin. 



quarter. The further course was somewhat variable, although 

 in most cases with a dose of 15 milligrams, or less, per kilo, 

 there was a rather sharp fall of temperature for thirty minutes 



