568 ACTION OF CURARE, ATROPINE, AND NICOTINE 



SUMMARY. 



1. The alkaloids (curare, atropine, and nicotine) in molluscs and 

 arthropods stimulate and paralyze the central nervous system and 

 peripheral (visceral) ganglia, but do not paralyze the motor nerve end- 

 ings to skeletal or visceral muscle. 



2. They stimulate and paralyze the denervated heart. 



3. They paralyze or block the cardioinhibitory nerves, but not the 

 cardioaccelerator nerves. 



4. In the Limulus heart these drugs act primarily on the heart 

 ganglion, not on the heart muscle or the intrinsic motor nerve fibers. 



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